Results 41 to 50 of about 443,480 (206)
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
, 2022 Orthologous matrices for constructing the phylogenetic tree.
Jia anqiang (13171782)
core +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Male figural rating scales: A critical review of the literature [PDF]
, 2020 Figural rating scales are tools used to measure male body dissatisfaction. The present review aimed to examine the design and psychometric properties of male figural rating scales and make recommendations based on findings.
Talbot, Daniel +2 more
core +2 more sources
Pairwise comparison matrices: an empirical research [PDF]
, 2011 Our research focused on testing various characteristics of pairwise comparison (PC) matrices in controlled experiments. About 270 students have been involved in the test exercises and the final pool contained 450 matrices.
Dezső, Linda +3 more
core +3 more sources
Model output and firing rates of neurons located on the figural region and on the background region.
, 2013 The light-dark squares in the centre column represent the NxN matrices of neurons of the model. The coloring of the matrices illustrates the membrane potential where light grey indicates high activity and dark grey zones low activity level.
August Romeo (330910) +2 more
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
, 2018 ©, Copyright © Taylor & Francis Group, LLC. To investigate the factor structure of the Figural Torrance Tests of Creative Thinking (Figural TTCT), a meta-confirmatory factor analysis was performed.
Fernandez-Castilla, Belen +4 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source