Results 61 to 70 of about 3,601,037 (276)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Figurativeness all the way down

, 2020
Figurative language is the outcome of our figurative thought, which derives from the ever-present interconnection between our physical experience and the relation we set up with the cultural context in which we live.
Baicchi, A., A. Baicchi, Baicchi, Annalisa Baicchi, Broccias, International Symposium on Figurative Thought and Language 2015 Pavia, Baicchi, Annalisa   +6 more
core   +1 more source

FIGURATIVE LANGUAGE IN EVANESCENCE’S ALBUM ANYWHERE BUT HOME [PDF]

, 2018
The research deals with figurative language, aimed to identify the types and interpret the ideas or messages implicitly or explicitly expressed with theoretical based proposed by Kennedy and Giola (2005) that figurative language is an expression of ...
Purwarno Purwarno, Sumarno Sumarno, Purwarno, Purwarno, Manugeren, M., M. Manugeren, Sumarno, Sumarno   +5 more
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

An Analysis of Figurative Language Elements upon an American Short Story Entitled “The Monkey’s Paw

JEES (Journal of English Educators Society), 2018
This article describes the study of semantic in a specified domain of figurative language upon a selected work of American English literature, in form of short story written by the renowned writer and author, William Wymark Jacobs, entitled as ‘The ...
Nur Muhammad Ardiansyah, Vidya Mandarani
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Producing figurative expression: theoretical, experimental and practical perspectives Figurative thought and language ;, v. 10./ edited by John Barnden, University of Birmingham ; Andrew Gargett, Open University.

, 2020
Includes bibliographical references and indexes."This collection contains a selection of recent work on people's production of figurative language (metaphoric, ironic, metonymic, hyperbolic, ...) and similarly of figurative expression in visual media and
Gargett Andrew D.,, Barnden John
core  

Semantic and Stylistic Features of Figurative Lexis in the Khanty Language (Based on Colloquial and Artistic Discourse)

Финно-угорский мир
Introduction. To date, in linguistics, the problem of separating figurative words from other expressive language units remains unresolved. The criteria according to which a given lexical unit is marked as figurative in an explanatory dictionary are ...
Andrey D. Kaksin
doaj   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

An Analysis of Figurative Language in Thomas Gray’s ‘Elegy Written in a Country Churchyard’

JL3T (Journal of Linguistics, Literature and Language Teaching)
Figurative language is one of intrinsic elements of a poem. The use of figurative language is intended to beautify expressions or sentences. The purpose of this research was to describe the types of figurative languages used by Thomas Gray in his poem ...
Ruly Adha
doaj   +1 more source