Improved Assessment of Globularity of Protein Structures and the Ellipsoid Profile of the Biological Assemblies From the PDB [PDF]
Biomolecules, 2023 In this paper, we present an update to the ellipsoid profile algorithm (EP), a simple technique for the measurement of the globularity of protein structures without the calculation of molecular surfaces.
Mateusz Banach
exaly +6 more sources
Crystals, 2021 A computer algorithm for assessment of globularity of protein structures is presented. By enclosing the input protein in a minimum volume ellipsoid (MVEE) and calculating a profile measuring how voxelized space within this shape (cubes on a uniform grid)
Mateusz Banach
exaly +4 more sources
No Country for Oldowan Men: Emerging Factors in Language Evolution [PDF]
Frontiers in Psychology, 2019 Language evolution has long been researched. I will review a number of broad, emerging research directions which arguably have the potential to contribute to our understanding of language evolution.
Elliot Murphy
exaly +5 more sources
Chromosomal Rearrangements and Protein Globularity Changes in Mycobacterium tuberculosis Isolates From Cerebrospinal Fluid [PDF]
PeerJ, 2016 Background Meningitis is a major cause of mortality in tuberculosis (TB). It is not clear what factors promote central nervous system invasion and pathology but it has been reported that certain strains of Mycobacterium tuberculosis (Mtb) might have ...
Yun Fong Ngeow +2 more
exaly +5 more sources
How Round Is a Protein? Exploring Protein Structures for Globularity Using Conformal Mapping [PDF]
Frontiers in Molecular Biosciences, 2014 We present a new algorithm that automatically computes a measure of the geometric difference between the surface of a protein and a round sphere. The algorithm takes as input two triangulated genus zero surfaces representing the protein and the round ...
Patrice Koehl, Joel Hass
exaly +4 more sources
Brain Asymmetry in the White Matter Making and Globularity [PDF]
Frontiers in Psychology, 2015 Recent studies from the field of language genetics and evolutionary anthropology have put forward the hypothesis that the emergence of our species-specific brain is to be understood not in terms of size, but in light of developmental changes that gave ...
Constantina Theofanopoulou
exaly +4 more sources
Crystal structure and Hirshfeld surface analysis of 2,6-bis[4-(ethoxycarbonyl)-5-methylpyrazol-1-yl]pyridine [PDF]
Acta Crystallographica Section E: Crystallographic CommunicationsThe title compound (systematic name: ethyl 1-{6-[4-(ethoxycarbonyl)-5-methylpyrazol-1-yl]pyridin-2-yl}-5-methylpyrazole-4-carboxylate), C19H21N5O4, consists of a central pyridine ring substituted by two functionalized pyrazole rings and crystallizes in ...
Yevhen Krokhmaliuk +5 more
doaj +2 more sources
Changes in infant head shape: Developmental trends during the first year of life and secular changes observed in recent years. [PDF]
PLoS ONEThe cephalic index (CI), defined as the percentage of head width to length, has been used in multiple studies. However, CI only provides 2D information, and comprehensive methods to assess the 3D cranial shape are yet to be established.
Eujin Lee +4 more
doaj +2 more sources
Frontiers in Psychology, 2014 This study builds on the hypothesis put forth in Boeckx and Benitez-Burraco (2014), according to which the developmental changes expressed at the levels of brain morphology and neural connectivity that resulted in a more globular braincase in our species
Cedric Boeckx, Antonio Benítez-Burraco
exaly +3 more sources
Deciphering Chemical Rules for Drug Penetration into Strongyloides [PDF]
PharmaceuticsBackground: Strongyloidiasis, a parasitic infection, presents a significant public health challenge in tropical regions due to the limited repertoire of effective treatments.
Miguel Marín +5 more
doaj +2 more sources