Results 51 to 60 of about 167,836,181 (301)

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source

Optimizing plasmonic nanostructures array for high-performance sensing applications

Results in Physics
The localized surface plasmon resonance (LSPR) phenomenon, influenced by the surrounding medium, has been widely employed in optical sensors. Traditional sensors focus on refractive index sensitivity (ηRIS) but neglect the broad spectral linewidth, thus ...
Sajid Farooq, Rashid Hussain Dahar, Muhammd Waqas Yasin, May Hu, Diego Rativa, Dexing Kong, Renato E. de Araujo   +6 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Heisenberg scaling based on population coding [PDF]

Quantum
We study Heisenberg scaling of quantum metrology in the viewpoint of population coding. Although Fisher information has been used for a figure of merit to characterize Heisenberg scaling in quantum metrology, several studies pointed out it does not work ...
Masahito Hayashi
doaj   +1 more source

Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy–Related Inflammation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify MRI predictors of relapse and quantify relapse and mortality risk in cerebral amyloid angiopathy–related inflammation (CAA‐RI). A secondary objective was to assess the association between mycophenolate mofetil use and relapse risk. Methods We performed a retrospective cohort study of 36 patients with CAA‐RI treated at the
G. Abbas Kharal, Gowtham Yerneni, Kim J. Griffin, Nicolas Thompson, Ken Uchino, Irene Katzan, Dolora Wisco, Abeer Farrag, Jayashree Sundarajan, Andrew Russman, M. Shazam Hussain   +10 more
wiley   +1 more source

Figure of merit for the optimization of wireless power transfer system against misalignment tolerance

, 2016
Optimization of wireless power transfer (WPT) systems with high performance and misalignment tolerance is investigated in this paper. Key performance indices of WPT are power transfer efficiency (PTE), transferred power (TP), and misalignment tolerance ...
Vilathgamuwa, D. Mahinda, Alphones, Arokiaswami, Sampath, Jayathurathnage Prasad K.   +2 more
core   +1 more source

Computational Study of the Electronic Performance of Cross-Plane Superlattice Peltier Devices [PDF]

, 2011
We use a state-of-the-art non-equilibrium quantum transport simulation code, NEMO- 1D, to address the device physics and performance benchmarking of cross-plane superlattice Peltier coolers.
Gerhard Klimeck, Lundstrom, M., Jeong, Changwook, Klimeck, Gerhard, Klimeck, G., Changwook Jeong, Mark Lundstrom, Lundstrom, Mark S.   +7 more
core   +1 more source

A phenomenological figure of merit for photovoltaic materials

JPhys Energy
I derive a figure of merit (FOM) $\Gamma_{\mathrm{PV}}$ to estimate the maximum efficiency attainable by a generic non-ideal photovoltaic (PV) absorber in a planar single-junction solar cell.
Andrea Crovetto
doaj   +1 more source

Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights From a Large International Sicca Registry

Arthritis Care &Research, EarlyView.
Objective The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögren's International Collaborative Clinical Alliance (SICCA) cohort. Methods We performed a retrospective analysis examining 16 ocular symptoms (most graded 0–4) and artificial tear (AT) use (graded 0–3) as predictors of DED signs (abnormal ocular ...
Pragnya R. Donthineni, Chloe Shields, Rohit Muralidhar, Shreya Bhatt, Alan Baer, Robert Fox, Sara S. McCoy, Anat Galor   +7 more
wiley   +1 more source