Results 61 to 70 of about 250,897 (289)

Environment Assisted Metrology with Spin Qubit [PDF]

, 2011
We investigate the sensitivity of a recently proposed method for precision measurement [Phys. Rev. Lett. 106, 140502 (2011)], focusing on an implementation based on solid-state spin systems. The scheme amplifies a quantum sensor response to weak external
A. S. Sørensen, G. Goldstein, J. R. Maze, J. S. Hodges, L. Jiang, M. D. Lukin, P. Cappellaro, U. Haeberlen   +7 more
core   +3 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Guided Mode Resonance Sensors with Optimized Figure of Merit

Nanomaterials, 2019
The guided mode resonance (GMR) effect is widely used in biosensing due to its advantages of narrow linewidth and high efficiency. However, the optimization of a figure of merit (FOM) has not been considered for most GMR sensors.
Yi Zhou, Bowen Wang, Zhihe Guo, Xiang Wu
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Combining Size and Shape in Weak Lensing

, 2013
Weak lensing alters the size of images with a similar magnitude to the distortion due to shear. Galaxy size probes the convergence field, and shape the shear field, both of which contain cosmological information.
Alsing, Justin, Heavens, Alan, Jaffe, Andrew   +2 more
core   +1 more source

NANOSTRUCTURING AS A WAY FOR THERMOELECTRIC EFFICIENCY IMPROVEMENT [PDF]

Научно-технический вестник информационных технологий, механики и оптики, 2014
The urgency of thermoelectric energy conversion is proved. Perspectives of nanostructures usage as thermoelectric materials are shown. The authors have systematized and generalized the methods and investigation results of bulk nanostructure ...
L. V. Bochkov, I. A. Nefedova, R. Ahiska
doaj  

Frictional Figures of Merit for Single Layered Nanostructures [PDF]

Physical Review Letters, 2012
We determined frictional figures of merit for a pair of layered honeycomb nanostructures, such as graphane, fluorographene, MoS$_2$ and WO$_2$ moving over each other, by carrying out ab-initio calculations of interlayer interaction under constant loading force.
Cahangirov, S., Ataca, C., Topsakal, M., Sahin, H., Ciraci, S.   +4 more
openaire   +8 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Coefficient of performance at maximum figure of merit and its bounds for low-dissipation Carnot-like refrigerators

, 2012
The figure of merit for refrigerators performing finite-time Carnot-like cycles between two reservoirs at temperature $T_h$ and $T_c$ ($
A. Calvo Hernández, I. Novikov, J. M. Gordon, J. M. M. Roco, J. Yvon, Mingxing Li, P. Chambadal, S. K. Ma, Yang Wang, Z. C. Tu   +9 more
core   +1 more source