Results 181 to 190 of about 5,739 (299)
Model Master File Framework: A Regulatory Path Advancing Modeling and Simulation Applications
ABSTRACT To advance drug product development, regulatory decision making, and improve patient care, FDA has committed to the quantitative medicine paradigm that involves, among others, quantitative in silico methodologies and tools developed based on nonclinical, clinical, and real‐world sources. In this Perspective, Model Master File (MMF) submissions
Eleftheria Tsakalozou +4 more
wiley +1 more source
Pleistocene chronology and history of hominins and fauna at Denisova Cave. [PDF]
Jacobs Z +17 more
europepmc +1 more source
This scoping review aimed to understand the construct ‘involvement’ in daily life activities from the perspective of children and young people with childhood‐onset disabilities. We identified six conceptual ideas, including a continuum of inner dedication or investment in‐the‐moment, and five others reflecting how children and young people process ...
Vera C Kaelin +4 more
wiley +1 more source
Assessment of Apple's object capture photogrammetry API for rapidly creating research quality cultural heritage 3D models. [PDF]
Hurst S, Franklin L, Johnson E.
europepmc +1 more source
Spontaneous Hepatobiliary Disease in a Breeding Colony of Aotus spp.
ABSTRACT Background Owl monkeys are nonhuman primate species in the genus Aotus. The Michale E. Keeling Center for Comparative Medicine and Research maintains an Owl Monkey Breeding and Research Resource composed of four species of owl monkeys: Aotus nancymai, A. vociferans, A. azarae, and A. griseimembra.
M. E. Hensel +4 more
wiley +1 more source
Electrical Spinal Imaging: A noninvasive, high-resolution approach that enables electrophysiological mapping of the human spinal cord. [PDF]
Gabrieli G +5 more
europepmc +1 more source
ABSTRACT Excess adiposity is not a recently developed problem but has existed since at least the upper Paleolithic, allowing evolutionary selection pressures to adapt the physiology of the pregnant woman and the feto‐placental unit for maternal and fetal protection.
Gernot Desoye +6 more
wiley +1 more source
SHORT HISTORY OF OBESITY. [PDF]
Micic D, Polovina S, Micic D, Yumuk VD.
europepmc +1 more source
ABSTRACT Schizophrenia (SZ) has been linked with a pessimistic future outlook but the specific factors influencing such outlook are still to be mapped out. SZ is often referred to as a self‐disorder and sense of self has been suggested to be a crucial factor influencing future view.
Majse Lind +3 more
wiley +1 more source

