Results 31 to 40 of about 308,694 (251)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Scientific Reports, 2022 As the pervasive, standardized format for interchange and deposition of raw mass spectrometry (MS) proteomics and metabolomics data, text-based mzML is inefficiently utilized on various analysis platforms due to its sheer volume of samples and limited ...
Jinyin Wang +5 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
ABOUT 3D PRINTING STL 2.0 FILE FORMAT [PDF]
Fiabilitate şi DurabilitateIn this paperwork is presented, based on comparison between different common 3D printing file formats, like STL, OBJ, AMF and 3MF, some characteristics, some limitation and future perspective of these file formats .In this line is presented the ...
Cătălin IANCU
doaj
Dataset for file fragment classification of audio file formats
BMC Research Notes, 2019 Objectives File fragment classification of audio file formats is a topic of interest in network forensics. There are a few publicly available datasets of files with audio formats.
Atieh Khodadadi, Mehdi Teimouri
doaj +1 more source
Implementasi Pengamanan MP3 Menggunakan Advanced Encryption Standard
Jurnal Masyarakat Informatika, 2019 Format MP3 merupakan salah satu format suara yang populer. Format ini tidak memiliki implementasi keamanan sehingga dapat menimbulkan beberapa dampak negatif. Salah satu dampak negatifnya adalah resiko terhadap keamanan MP3 yang berisi informasi rahasia.
Ismaya Khusnu Wicaksana +2 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
BD5: An open HDF5-based data format to represent quantitative biological dynamics data.
PLoS ONE, 2020 BD5 is a new binary data format based on HDF5 (hierarchical data format version 5). It can be used for representing quantitative biological dynamics data obtained from bioimage informatics techniques and mechanobiological simulations. Biological Dynamics
Koji Kyoda +4 more
doaj +1 more source
BMC Bioinformatics, 2023 Background An updated version of the mwtab Python package for programmatic access to the Metabolomics Workbench (MetabolomicsWB) data repository was released at the beginning of 2021. Along with updating the package to match the changes to MetabolomicsWB’
Christian D. Powell +1 more
doaj +1 more source