Results 51 to 60 of about 295,131 (255)

Identification of fragmented JPEG files in the absence of file systems [PDF]

2015 IEEE Conference on Open Systems (ICOS), 2015
Identifying fragmented and deleted files from scattered digital storage become crucial needs in computer forensic. Storage media experience regular space fragmentation which gives direct consequence to the files system series. This paper specifies a case where the jpeg files are heavily fragmented with absent file header which contains maximum ...
Abdul Kadir, Nur Fasihah, Abd Razak, Shukor, Chizari, Hassan   +2 more
openaire   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Evaluating a File-Based Event Builder to enhance the Data Acquisition in the CMS Experiment [PDF]

EPJ Web of Conferences
The event builder in the Data Acquisition System (DAQ) of the CMS experiment at the CERN Large Hadron Collider (LHC) is responsible for assembling events at a rate of 100 kHz during the current LHC run 3, and up to750 kHz for the upcoming High Luminosity
Alawieh Jaafar, Arutjunjan Kareen, Bacharov Durasov Miguel, Behrens Ulf, Bocci Andrea, Branson James, Brummer Philipp Maximilian, Bugajski Jan Andrzej, Cano Eric, Cittolin Sergio, Corominas I Mariscot Albert, Darlea Georgiana-Lavinia, Deldicque Christian, Dobson Marc, Dvorak Antonin, Emmanouil Christos, Gaile Antra, Gigi Dominique, Glege Frank, Gomez-Ceballos Guillelmo, Gorniak Patrycja, Hegeman Jeroen, Izquierdo Moreno Guillermo, James Thomas Owen, Jayakumar Tejeswini, Karimeh Wassef, Krawczyk Rafał, Li Wei, Long Kenneth, Meijers Frans, Meschi Emilio, Morović Srećko, Odetayo Babatunde John, Orsini Luciano, Paus Christoph, Petrucci Andrea, Pieri Marco, Rabady Dinyar Sebastian, Racz Attila, Rizopoulos Theodoros, Sakulin Hannes, Schwick Christoph, Šimelevičius Dainius, Tzanis Polyneikis, Vazquez Velez Cristina, Žejdl Petr   +45 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Fragmentation patterns of forest and cerrado vegetation in northeastern Mato Grosso

Revista Agrogeoambiental, 2022
This study sought to evaluate the fragmentation patterns of the forest and cerrado vegetation in the northeast of the state of Mato Grosso. The investigation used landscape metrics after extracting those fragments from the shapefile of soil use and ...
Raphael Maia Aveiro Cessa, Uirá do Amaral, Felipe Gimenes Rodrigues Silva, Nilton Nélio Cometti   +3 more
doaj  

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

The key security management scheme of cloud storage based on blockchain and digital twins

Journal of Cloud Computing: Advances, Systems and Applications
As a secure distributed ledger technology, blockchain has attracted widespread attention from academia and industry for its decentralization, immutability, and traceability characteristics.
Jie Huang, Jiangyi Yi
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source