Results 51 to 60 of about 98,079 (258)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Facial Rejuvenation: An Evolving World

open access: yesDelhi Journal of Ophthalmology, 2016
The demand for facial rejuvenation has now spread from celebrites to common man. Complete facial rejuvenation not only refers to surgery, but also skin optimization.
Shubhra Goel
doaj   +1 more source

Experiment and Simulation Study of the Effect of Fillers on Mechanical Properties of Sustainable Composite

open access: yesJournal of Mechanical Engineering, 2022
Natural fiber reinforced polymer matrix composites are gaining increasing attention as engineering materials for advanced applications, including high performance ballistic armor components. This requires superior mechanical properties, such as toughness.
Zaini Mohammed   +4 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

A Historical Perspective on Dental Composite Restorative Materials

open access: yesJournal of Functional Biomaterials
This review article will discuss the origin of resin-based dental composite materials and their adoption as potentially useful adjuncts to the primary material used by most dentists for direct restorations.
Jack L. Ferracane
doaj   +1 more source

Tapped density optimisation for four agricultural wastes - Part I: Taguchi technique and mean response determination [PDF]

open access: yesActa Periodica Technologica, 2016
Environmental concerns are being intensified in composite manufacturing ventures, using agricultural fillers as strategic materials to improve environmentally-conscious performance.
Ajibade Oluwaseyi Ayodele   +2 more
doaj   +1 more source

Nobel Laureates 1901-2023

open access: yes
A dataset containing a list of Nobel Prize recipients from 1901-2023 along with several pieces of information about each award such as field, reasoning, age/gender of the recipient ...
James Fillers
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

On the influence on the efficiency of anti-shrinkage additives superplasticizer

open access: yesИнженерно-строительный журнал, 2014
Cement paste shrinkage and influence of the shrink-resistant additive Estrifan Additive RCL on this process were studied, both when the latter one was used independently, and in a combination with the superplasticizer Muraplast FK48, and powdery fillers -
Yu.G. Barabanshchikov   +2 more
doaj   +1 more source

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