Results 61 to 70 of about 98,079 (258)

Sherlock Holmes Short Stories

open access: yes
This dataset contains individual text files for each Sherlock Holmes short story written by Sir Arthur Conan Doyle (56 ...
Fillers, James Thomas
core   +1 more source

Skin rejuvenation without a scalpel. I. Fillers.

open access: yes, 2006
Item does not contain fulltextFillers are an important tool in the armamentarium of the physician combating aging phenomena. A wide variety of filler substances are now available that meet many, but by far not all, needs in aesthetic medicine.
Haneke, E.   +2 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Fillers '86

open access: yes, 1986
SIGLEAvailable from British Library Document Supply Centre- DSC:86/05894(Fillers) / BLDSC - British Library Document Supply CentreGBUnited ...
British Plastics Federation, London (United Kingdom)   +1 more
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

The tribological behaviour of glass filled polytetrafluoroethylene(PTFE) under dry and water lubrication [PDF]

open access: yes, 2003
Includes bibliographical references.This study was aimed at establishing the tribological behaViour of 25 % wt glass fibre filled polytetrafluoroethylene (PTFE) under dry sliding conditions.
Klaas, Nkosana V
core   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

Experience of introduction of fine-grained concrete when producing road plates

open access: yesИнженерно-строительный журнал, 2014
In this paper an example of introduction of fine-grained concrete in production of ferroconcrete products is reviewed. The study is important because a high-quality material can be obtained with the use of local raw materials.
N.M. Krasinikova   +3 more
doaj   +1 more source

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