Results 31 to 40 of about 98,917 (314)

Experimental Investigation Into Unsteady Effects on Film Cooling

Volume 4: Heat Transfer, Parts A and B, 2010
The benefits of different film cooling geometries are typically assessed in terms of their time averaged performance. It is known that the mixing between the coolant film and the main turbine passage flow is an unsteady process. The current study investigates the forms of unsteadiness which occur in engine-representative film cooling flows, and how ...
Fawcett, R, Wheeler, A, He, L, Taylor, R, ASME   +4 more
openaire   +4 more sources

A simulation of film cooling in the leading edge region of a turbine blade (trench effect on film effectiveness from cylinder in crossflow) [PDF]

, 2012
Film cooling is one of the cooling system techniques applied to the turbine blade. Gas turbine use film cooling technique to protect turbine blade from expose directly to a hot gas to avoid the blade from defect.
Pairan, Mohamad Rasidi
core  

Curvature Effects on Discrete-Hole Film Cooling [PDF]

Volume 4: Heat Transfer; Electric Power; Industrial and Cogeneration, 1998
A numerical study has been conducted to investigate the effects of surface curvature on cooling effectiveness using three-dimensional film cooling geometries that included the mainflow, injection hole, and supply plenum regions. Three surfaces were considered in this study, namely, convex, concave, and flat surfaces.
M. K. Berhe, S. V. Patankar
openaire   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Near-Field Simulations of Film Cooling with a Modified DES Model

Inventions, 2020
Modeling the heat transfer characteristics of highly turbulent flow in gas turbine film cooling is important for providing better insights and engineering solutions to the film cooling problem. This study proposes a modified detached eddy simulation (DES)
Feiyan Yu, Savas Yavuzkurt
doaj   +1 more source

Effect of spherical blockage configurations on film cooling

Thermal Science, 2018
With increasing inlet temperature of gas turbines, turbine blades need to be effectively protected by using cooling technologies. However, the deposition from the fuel impurities and dust particles in the air is often found inside film holes, which results in partial hole blockage.
Wang, Jin, Ke, Tian, Zhang, Kai, Baleta, Jakov, Sundén, Bengt   +4 more
openaire   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Computational study of plasma actuator on film cooling performance for different shaped holes

AIP Advances, 2015
An investigation on film cooling holes with plasma actuators are performed for circular hole, expansion-shaped hole and fan-shaped hole on the surface of flat plate.
Sheng-ji Dai, Yang Xiao, Li-ming He, Tao Jin, Peng-hui Hou, Qian Zhang, Zi-chen Zhao   +6 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source