Results 111 to 120 of about 4,076,651 (345)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Fuzzy filters

open access: yesJournal of Mathematical Analysis and Applications, 1988
Let X be a set and I the unit interval. In fuzzy topology, subsets of X (which can be identified with mappings from X to \(\{\) 0,1\(\})\) are replaced by so-called fuzzy sets (which by definition, are mappings from X to I). In the same spirit, topological concepts defined in terms of the lattice structure on \({\mathfrak P}(X)\) (ordered by \(A\subset
de Prada Vicente, M.A.   +1 more
openaire   +2 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

The maximality of filters

open access: yesJournal of Pure and Applied Algebra, 1990
This beautifully written and interesting paper deals with constructive characterization of prime filters on a Boolean algebra and of prime filters on a compact regular locale, both in an arbitrary topos. As such characterizations are stated in terms of maximality of the filters in question, they could hold without the assumption that the topos is a De ...
openaire   +3 more sources

Filteration Tests Geotextile Filters

open access: yesProceedings of geotextile symposium, 1993
Geotextile are utltized for prevention of soil draw out and filtration material. However testing methods and quality standards have not been established yet in Japen. So, we proposed new test methods for geotextile filtration applicability.Those methods of testing are; A. O.
Yoshiyuki Hayashi   +6 more
openaire   +3 more sources

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Adaptive acoustooptic filter [PDF]

open access: yes, 1984
A new adaptive filter utilizing acoustooptic devices in a space integrating architecture is described. Two configurations are presented; one of them, suitable for signal estimation, is shown to approximate the Wiener filter, while the other, suitable for
Hong, John, Psaltis, Demetri
core  

Home - About - Disclaimer - Privacy