Results 101 to 110 of about 1,700,069 (268)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Adaptive two-pass rank order filter to remove impulse noise in highly corrupted images [PDF]

open access: yes, 2004
This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services. Internal or personal use of this material is permitted.
Miller, E L   +7 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Digital IIR filter design using particle swarm optimisation [PDF]

open access: yes, 2010
Adaptive infinite-impulse-response (IIR) filtering provides a powerful approach for solving a variety of practical signal processing problems. Because the error surface of IIR filters is typically multimodal, global optimisation techniques are generally ...
Chen, Sheng, Luk, Bing L.
core  

Computation of the para-pseudoinverse for oversampled filter banks: Forward and backward Greville formulas [PDF]

open access: yes, 2008
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2008 IEEE. Personal use of this material is permitted.
Cong Ling   +6 more
core   +1 more source

Clustering in Celebrating Professor Themba A. Dube (A TAD Celebration II) [PDF]

open access: yesCategories and General Algebraic Structures with Applications
This paper is the second in the series celebrating the mathematical works of Professor Themba Dube. In this sequel, we give prominence to Dube's pivotal contributions on pointfree convergence at the unstructured frame level, in the category of locales ...
Inderasan Naidoo
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Understanding the Kalman Filter: an Object Oriented Programming Perspective. [PDF]

open access: yes
The basic ideals underlying the Kalman filter are outlined in this paper without direct recourse to the complex formulae normally associated with this method. The novel feature of the paper is its reliance on a new algebraic system based on the first two
Snyder, R.D., Forbes, C.S.
core  

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