Results 81 to 90 of about 1,891,525 (289)
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Journal of New Theory, 2017 This paper deals the notion of Ω −N -structured subalgebras and Ω−N -structured Filters on CI-algebra.
Prakasam Muralikrishna +1 more
doaj
Indian Journal of Ophthalmology, 2014 Aim: The aim was to ascertain if any differences exist in diurnal central corneal thickness (CCT) and intra-ocular pressure (IOP) between eyes with pseudoexfoliation (PXF) syndrome without glaucoma and eyes with no ocular pathology.
Stuart Keel +2 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Design and Fabrication of Two-Filter Nano SL Mask to Deal with Covid-19
JLUMHS, 2021 OBJECTIVE: These days, due to the spread of infectious diseases such as COVID-19 and influenza, as well as the increase in air pollutants, the use of a face mask has become a necessity.
Sajjad Pashaie +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Independent Filter Company Advertisement, 1899
, 1899 This document is an illustrated advertisement for the Theurer Beer Filter. This filter was created and patented by the Independent Filter Company in 1899.
Independent Filter Company;
core
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Clustering in Celebrating Professor Themba A. Dube (A TAD Celebration II) [PDF]
Categories and General Algebraic Structures with ApplicationsThis paper is the second in the series celebrating the mathematical works of Professor Themba Dube. In this sequel, we give prominence to Dube's pivotal contributions on pointfree convergence at the unstructured frame level, in the category of locales ...
Inderasan Naidoo
doaj +1 more source