Results 71 to 80 of about 1,891,525 (289)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Numerical simulation of side intake flow of a gas turbine
[Objectives] This paper studies the influence of wind direction on the stability,evenness and loss of flow resistance of the side intake flow of a gas turbine.[Methods] CFX is applied to make numerical simulation of the intake flow of the gas turbine ...
YANG Jian +5 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Tunable ring resonator filter for OFDM Transmission systems [PDF]
A novel tunable filter is theoretically demonstrated. It is based on a ring resonator with an amplifier and a noise filter in the loop. This optoelectronic device has potential as a high-sensitivity receiver and as a tunable demultiplexer in OFDM ...
López Amo, Manuel +2 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Introduction: One of the problems that the delivery of continuous positive airway pressure (CPAP) via a helmet poses is the generation of noise. The objective of our study was to assess the effect that the use of filter has on sound pressure levels ...
Ricardo Hernández-Molina +4 more
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
An 'active' passive-filter topology for low power DC/AC inverters [PDF]
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis presents a new output passive filter for voltage source inverter applications which is based on a shunt connected single tuned filter topology ...
Arman, Mahmoud Fayez
core +4 more sources

