Results 131 to 140 of about 4,190,276 (347)

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Research of sub-channel filter technique in the digital channelization

open access: yesTongxin xuebao, 2017
In the satellite communications,there were very high performance requirements for the satellite transponder due to the restrictions of the volume and weight of the load,and the satellite channelization technique was an important means to solve this ...
Di HE   +5 more
doaj  

Application of the Savitzky-Golay-Filter to analyze the energy-loss of a heavy ion beam in an X-ray-heated CHO-foam

open access: green, 2015
R. Maeder   +8 more
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Efficiency of Protective Mask Filters in Removal of Hexavalent Chromium Mist

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2012
BACKGROUND AND OBJECTIVE: Personal protective equipments (PPE) are common equipments for control of workers exposure to harmful agents in work environment. Regarding to the critical role of the filter collection efficiency under hazardous conditions such
F Golbabaei,   +4 more
doaj  

Filtered screens and augmented Teichmüller space [PDF]

open access: green, 2015
Douglas J. LaFountain, R. C. Penner
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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