Results 51 to 60 of about 3,717,413 (296)

Performance Evaluation of a Proposed Machine Learning Model for Chronic Disease Datasets Using an Integrated Attribute Evaluator and an Improved Decision Tree Classifier

Applied Sciences, 2020
There is a consistent rise in chronic diseases worldwide. These diseases decrease immunity and the quality of daily life. The treatment of these disorders is a challenging task for medical professionals.
Sushruta Mishra, Pradeep Kumar Mallick, Hrudaya Kumar Tripathy, Akash Kumar Bhoi, Alfonso González-Briones   +4 more
doaj   +1 more source

Tunable Graphene Antennas for Selective Enhancement of THz-Emission [PDF]

, 2013
In this paper, we will introduce THz graphene antennas that strongly enhance the emission rate of quantum systems at specific frequencies. The tunability of these antennas can be used to selectively enhance individual spectral features.
Alaee, R., Farhat, M., Filter, R., Lederer, F., Rockstuhl, C., Steglich, M.   +5 more
core   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Antimicrobial s-PBC Coatings for Innovative Multifunctional Water Filters

Molecules, 2020
Biological contamination is a typical issue in water treatment. Highly concentrated microbial suspensions in a water flow may cause filter occlusion and biofilm formation, affecting the lifespan and quality of water purification systems and increasing ...
Emanuele Luigi Sciuto, Simona Filice, Maria Anna Coniglio, Giuseppina Faro, Leon Gradon, Clelia Galati, Natalia Spinella, Sebania Libertino, Silvia Scalese   +8 more
doaj   +1 more source

Sampler of gas borne particles [PDF]

, 1976
An atmosphere sample is described which includes a very thin filter element with straight-through holes on the order of 1 micron. A sample of air with particles to be examined is driven by means of a pressurized low molecular weight gas, e.g., He to the ...
Miller, C. G., Stephens, J. B.
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Efficiency and hydraulic performance of the micro-pressure filter in front of the pump studied using PPR and NSGA-II

Guan'gai paishui xuebao
【Objective】 Pump often has a filter installed in the front of it to filter sediments and debris. This paper studied its efficiency and performance. 【Method】 The study was based on physical model, with flow rate being 2-8 m3/h, sediment content being 0.5 ...
TAO Hongfei, LI Qi, ZHOU Yang, Mahemujiang ·Aihemaiti, LI Qiao, JIANG Youwei   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source