Results 51 to 60 of about 297,748 (266)

Accelerating Haze Removal Algorithm Using CUDA

open access: yesRemote Sensing, 2020
The dark channel prior (DCP)-based single image removal algorithm achieved excellent performance. However, due to the high complexity of the algorithm, it is difficult to satisfy the demands of real-time processing. In this article, we present a Graphics
Xianyun Wu   +4 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Filtering algorithms for global chance constraints

open access: yesArtificial Intelligence, 2012
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Brahim Hnich   +3 more
openaire   +5 more sources

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Strong Tracking Spherical Simplex-Radial Cubature Kalman Filter for Maneuvering Target Tracking

open access: yesSensors, 2017
Conventional spherical simplex-radial cubature Kalman filter (SSRCKF) for maneuvering target tracking may decline in accuracy and even diverge when a target makes abrupt state changes.
Hua Liu, Wen Wu
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Filtering algorithms for the multiset ordering constraint

open access: yesArtificial Intelligence, 2009
Constraint programming (CP) has been used with great success to tackle a wide variety of constraint satisfaction problems which are computationally intractable in general. Global constraints are one of the important factors behind the success of CP. In this paper, we study a new global constraint, the multiset ordering constraint, which is shown to be ...
Alan M. Frisch   +4 more
openaire   +3 more sources

An Optimal Filtering Algorithm for Table Constraints [PDF]

open access: yes, 2012
Filtering algorithms for table constraints are constraint-based, which means that the propagation queue only contains information on the constraints that must be reconsidered. This paper proposes four efficient value-based algorithms for table constraints, meaning that the propagation queue also contains information on the removed values.
Mairy, Jean-Baptiste   +3 more
openaire   +2 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Design method of nonsubsampled graph filter banks

open access: yesDianzi Jishu Yingyong, 2019
In order to overcome the problem that it is difficult to accurately define the downsampling operation for a generalized graph signal in graph filter banks, this paper focuses on the design algorithm of nonsubsampled graph filter banks.
Yang Sheng
doaj   +1 more source

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