Results 41 to 50 of about 7,575 (261)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Filtering Antenna With Two-Octave Harmonic Suppression [PDF]

IEEE Antennas and Wireless Propagation Letters, 2017
A novel 2nd–order antenna with filtering performance and two-octave harmonic suppression is proposed. In order to reduce the effects of the harmonics of the antenna, two types of antennas (PIFA and patch) with different resonant characteristics are integrated into the design.
Mao, Chun-Xu, Gao, Steven, Wang, Yi, Cheng, Zhiqun   +3 more
openaire   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Integration Design of Millimeter-Wave Filtering Patch Antenna Array With SIW Four-Way Anti-Phase Filtering Power Divider

IEEE Access, 2019
In this paper, the integration design of a millimeter-wave filtering patch antenna array fed by a substrate integrated waveguide (SIW) four-way anti-phase filtering power divider is proposed.
Huayan Jin, Guo Qing Luo, Wenlei Wang, Wenquan Che, Kuo-Sheng Chin   +4 more
doaj   +1 more source

Low-profile dual-polarized differential-fed filtering antenna and its novel array with low sidelobe level

Engineering Science and Technology, an International Journal, 2023
This paper presents a single-layer dual-polarized filtering antenna with good out-of-band suppression. By using inherent characteristic of the patch’s eigenmode and meanwhile merging four filtering strategies, i.e., parasitic patches, slot on the driving
Quanwei Wu, Yan Shi, Long Li
doaj   +1 more source

Compact Differential-Fed Planar Filtering Antennas [PDF]

Electronics, 2019
This paper proposes novel low-profile differential-fed planar antennas with embedded sharp frequency selectively. The antennas are compact and easy to integrate with differential devices without matching baluns. The antenna design is formulated as a topology optimization problem, where requirements on impedance bandwidth, directivity, and filtering are
Emadeldeen Hassan, Denys Martynenko, Eddie Wadbro, Gunter Fischer, Martin Berggren   +4 more
openaire   +3 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Metamaterial conical beam antenna with dual band filtering response

Scientific Reports
A novel conical beam antenna with dual band filtering response is proposed by utilizing a metamaterial (MTM). The dual band filtering characteristics are inherently derived from the MTM and achieved through the coaxial feed and the probe coupling ...
Xianfeng Tang, Junli Lu, Xiangqiang Li, Che Xu, Qingfeng Wang, Jianqiong Zhang   +5 more
doaj   +1 more source

Low-Profile Filtering End-Fire Antenna Integrated With Compact Bandstop Filtering Element for High Selectivity

IEEE Access, 2019
A high-selectivity low-profile filtering end-fire antenna is proposed using a bandstop filtering (BSF) element integrated into the feedline of the conventional quasi-Yagi antenna. Three transmission zeros (TZs) and six transmission poles (TPs) of the BSF
Kai-Da Xu, Han Xu, Yanhui Liu
doaj   +1 more source