Results 131 to 140 of about 763,836 (318)
Introduction. RIFLE and AKIN provide a standardised classification of acute kidney injury (AKI), but their categorical rather than continuous nature restricts their use to a research tool. A more accurate real-time description of renal function in AKI is
Iain A. M. MacPhee +5 more
core +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
The impact of electrostatic precipitation as a useful form of particulate filtration in the breathing zone is investigated in an intervention study in an air-conditioned commercial office in central London.
Young, A. +9 more
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
The research presented here is summary two years of studying the Biosand filter (BSF) both in Haiti during March 2011 and in the laboratory. In Chapter 2, we examined the long term use and sustainability 55 BSF systems near Deschapelles, Haiti and 47 ...
Sisson, Andrew John
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Solid-Liquid Filtration Practical Guides in Chemical Engineering
Practical Guides in Chemical Engineering are a cluster of short texts that each provides a focused introductory view on a single subject. The full library spans the main topics in the chemical process industries that engineering professionals require a ...
Perlmutter, Barry
core
Including filter media heterogeneities in the simulation of filtration processes
S.777-785The design of filter media is an important issue to meet the requirements of todays filtration processes. The media have to be optimized in terms of pressure loss, capturing efficiency, and dust holding capacity.
Kirsch, Ralf +4 more
core

