Results 21 to 30 of about 31,924 (207)

Diversity in Genetic Regulation of Bacterial Fimbriae Assembled by the Chaperone Usher Pathway

International Journal of Molecular Sciences, 2022
Bacteria express different types of hair-like proteinaceous appendages on their cell surface known as pili or fimbriae. These filamentous structures are primarily involved in the adherence of bacteria to both abiotic and biotic surfaces for biofilm formation and/or virulence of non-pathogenic and pathogenic bacteria.
Dharmender K. Gahlot, Nayyer Taheri, Sheila MacIntyre   +2 more
openaire   +4 more sources

Comparative proteomics of uropathogenic Escherichia coli during growth in human urine identify UCA-like (UCL) fimbriae as an adherence factor involved in biofilm formation and binding to uroepithelial cells [PDF]

, 2015
Uropathogenic Escherichia coli (UPEC) are the primary cause of urinary tract infection (UTI) in humans. For the successful colonisation of the human urinary tract, UPEC employ a diverse collection of secreted or surface-exposed virulence factors ...
Allsopp, LP, Moriel, DG, Schembri, MA, Totsika, M, Webb, RI, Wurpel, DJ   +5 more
core   +1 more source

A multivalent vaccine candidate targeting enterotoxigenic Escherichia coli fimbriae for broadly protecting against porcine post-weaning diarrhea

Veterinary Research, 2020
Fimbriae-mediated initial adherence is the initial and critical step required for enterotoxigenic Escherichia coli (ETEC) infection. Therefore, vaccine candidates have been developed that target these fimbriae and induce specific anti-fimbriae antibodies
Qiangde Duan, Shengmei Pang, Wenwen Wu, Boyu Jiang, Weiping Zhang, Siguo Liu, Xiaojun Wang, Zhiming Pan, Guoqiang Zhu   +8 more
doaj   +1 more source

Role of yqiC in the pathogenicity of Salmonella and innate immune responses of human intestinal epithelium

Frontiers in Microbiology, 2016
The yqiC gene of Salmonella enterica serovar Typhimurium (S. Typhimurium) regulates bacterial growth at different temperatures and mice survival after infection. However, the role of yqiC in bacterial colonization and host immunity remains unknown.
Ke-Chuan Wang, Ke-Chuan Wang, Chih-Hung Huang, Shih-Min Din, Ching-Kuo Chen, Hsu-Wei Fang, Hsu-Wei Fang, Ming-Te Huang, Ming-Te Huang, Shiuh-Bin Fang, Shiuh-Bin Fang   +10 more
doaj   +1 more source

P-fimbriae, bacterial adhesion, and pyelonephritis. [PDF]

Archives of Disease in Childhood, 1984
L'aptitude des agents pathogenes a adherer aux membranes muqueuses est maintenant reconnue comme un facteur potentiel de virulence; elle est souvent en rapport avec la presence de filaments proteiniques capables de reconnaitre des recepteurs, souvent glucidiques sur les membranes des cellules epitheliales.
openaire   +2 more sources

Discovery of Bacterial Fimbria–Glycan Interactions Using Whole-Cell Recombinant Escherichia coli Expression

mBio, 2021
Understanding the tropism of pathogens for host and tissue requires a complete understanding of the host receptors targeted by fimbrial adhesins. Furthermore, blocking adhesion is a promising strategy to counter increasing antibiotic resistance and is enabled by the identification of host receptors.
Christopher J. Day, Alvin W. Lo, Lauren E. Hartley-Tassell, M. Pilar Argente, Jessica Poole, Nathan P. King, Joe Tiralongo, Michael P. Jennings, Mark A. Schembri   +8 more
openaire   +4 more sources

Fimbriae assisted bacterial surface display of heterologous peptides

International Journal of Medical Microbiology, 2000
The display of peptide segments on the surface of bacteria offers many new and exciting applications in biotechnology and medical research. Fimbria-assisted display of heterologous sequences is a paradigm for chimeric organelle display on bacteria. Fimbriae are particularly attractive candidates for epitope display for several reasons: (1) they are ...
Klemm, P., Schembri, M.A.
openaire   +2 more sources

EtcABC, a Putative EII Complex, Regulates Type 3 Fimbriae via CRP-cAMP Signaling in Klebsiella pneumoniae

Frontiers in Microbiology, 2019
Biofilm formation by Klebsiella pneumoniae on indwelling medical devices increases the risk of infection. Both type 1 and type 3 fimbriae are important factors in biofilm formation by K. pneumoniae. We found that a putative enzyme II (EII) complex of the
Novaria Sari Dewi Panjaitan, Yu-Tze Horng, Shih-Wen Cheng, Wen-Ting Chung, Po-Chi Soo, Po-Chi Soo   +5 more
doaj   +1 more source

Type 3 Fimbriae Encoded on Plasmids Are Expressed from a Unique Promoter without Affecting Host Motility, Facilitating an Exceptional Phenotype That Enhances Conjugal Plasmid Transfer. [PDF]

PLoS ONE, 2016
Horizontal gene transfer (HGT), the transmission of genetic material to a recipient that is not the progeny of the donor, is fundamental in bacterial evolution.
Jonas Stenløkke Madsen, Leise Riber, Witold Kot, Alrun Basfeld, Mette Burmølle, Lars Hestbjerg Hansen, Søren Johannes Sørensen   +6 more
doaj   +1 more source

Chaperone-tip adhesin complex is vital for synergistic activation of CFA/I fimbriae biogenesis.

PLoS Pathogens, 2020
Colonization factor CFA/I defines the major adhesive fimbriae of enterotoxigenic Escherichia coli and mediates bacterial attachment to host intestinal epithelial cells.
Li-Hui He, Hao Wang, Yang Liu, Mei Kang, Tao Li, Chang-Cheng Li, Ai-Ping Tong, Yi-Bo Zhu, Ying-Jie Song, Stephen J Savarino, Michael G Prouty, Di Xia, Rui Bao   +12 more
doaj   +2 more sources