Results 31 to 40 of about 20,120 (184)

Bacterial cyclic AMP-phosphodiesterase activity coordinates biofilm formation. [PDF]

PLoS ONE, 2013
Biofilm-related infections are a major contributor to human disease, and the capacity for surface attachment and biofilm formation are key attributes for the pathogenesis of microbes. Serratia marcescens type I fimbriae-dependent biofilms are coordinated
Eric J Kalivoda, Kimberly M Brothers, Nicholas A Stella, Matthew J Schmitt, Robert M Q Shanks   +4 more
doaj   +1 more source

Evolutionary Analysis Points to Divergent Physiological Roles of Type 1 Fimbriae in Salmonella and Escherichia coli

mBio, 2013
Salmonella and Escherichia coli mannose-binding type 1 fimbriae exhibit highly similar receptor specificities, morphologies, and mechanisms of assembly but are nonorthologous in nature, i.e., not closely related evolutionarily.
Dagmara I. Kisiela, Sujay Chattopadhyay, Veronika Tchesnokova, Sandip Paul, Scott J. Weissman, Irena Medenica, Steven Clegg, Evgeni V. Sokurenko   +7 more
doaj   +1 more source

Discovery of Bacterial Fimbria–Glycan Interactions Using Whole-Cell Recombinant Escherichia coli Expression

mBio, 2021
Understanding the tropism of pathogens for host and tissue requires a complete understanding of the host receptors targeted by fimbrial adhesins. Furthermore, blocking adhesion is a promising strategy to counter increasing antibiotic resistance and is enabled by the identification of host receptors.
Christopher J. Day, Alvin W. Lo, Lauren E. Hartley-Tassell, M. Pilar Argente, Jessica Poole, Nathan P. King, Joe Tiralongo, Michael P. Jennings, Mark A. Schembri   +8 more
openaire   +6 more sources

Phenotypic Characterization of Porphyromonas gulae Fimbria Mutants

Cellular Microbiology
Porphyromonas gulae has been established as a pathogen in animal periodontal disease and expresses several virulence factors, including fimbriae, lipopolysaccharide, and proteases. P. gulae fimbriae are classified into three genotypes (A, B, and C) based
Hiroaki Inaba, Sho Yoshida, Naoya Ohara, Ryota Nomura, Kazuhiko Nakano, Michiyo Matsumoto-Nakano   +5 more
doaj   +1 more source

PapB Family Regulators as Master Switches of Fimbrial Expression

Microorganisms
Some bacterial species within the Enterobacteriaceae family possess different types of fimbrial (pili) adhesins that promote adherence to cells and colonization of host tissues.
Fariba Akrami, Hossein Jamali, Mansoor Kodori, Charles M. Dozois   +3 more
doaj   +1 more source

Std fimbriae-fucose interaction increases Salmonella-induced intestinal inflammation and prolongs colonization.

PLoS Pathogens, 2019
Expression of ABO and Lewis histo-blood group antigens by the gastrointestinal epithelium is governed by an α-1,2-fucosyltransferase enzyme encoded by the Fut2 gene.
Abdulhadi Suwandi, Alibek Galeev, René Riedel, Samriti Sharma, Katrin Seeger, Torsten Sterzenbach, Lucía García Pastor, Erin C Boyle, Ohad Gal-Mor, Michael Hensel, Josep Casadesús, John F Baines, Guntram A Grassl   +12 more
doaj   +1 more source

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

Advanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang, Peichao Zhang, Simin Gu, Hongyun Lu, Ningning Jiang, Jiarun Zhao, Enbo Xu, Xiayu Liu, Ying Shi, Qihe Chen   +9 more
wiley   +1 more source

Subversion of a family of antimicrobial proteins by Salmonella enterica

Frontiers in Cellular and Infection Microbiology
Salmonella enterica is a food-borne pathogen able to cause a wide spectrum of diseases ranging from mild gastroenteritis to systemic infections. During almost all stages of the infection process Salmonella is likely to be exposed to a wide variety of ...
Roman G. Gerlach, Roman G. Gerlach, Irene Wittmann, Lena Heinrich, Olaf Pinkenburg, Torben Meyer, Laura Elpers, Christiane Schmidt, Michael Hensel, Markus Schnare   +9 more
doaj   +1 more source

Analisis Antibodi IgG Spesifik Fimbria Porphyromonas gingivalis dengan Metoda Elisa pada Penderita Early-Onset Periodontitis

Journal of Dentistry Indonesia, 2015
The adherence of bacteria to the host tissues is a first step in the development of infections. Bacterial fimbriae have been shown to play an important role in the interaction between bacteria and host cells or among bacterial cells.
Dewi Nurul Mustaqimah, Irene Sukardi, Yoneda Masahiro, K. Maeda   +3 more
doaj   +1 more source

Beyond antimicrobials: Ecological nano‐strategies for rebalancing dysbiotic oral microbial homeostasis

BMEMat, EarlyView.
Oral microbial homeostasis, a dynamic host‐microbe balance, is vital in infectious diseases. Conventional antibiotics often disrupt this homeostasis, spurring interest in nanomaterials for oral microbial homeostasis rebalancing. This review outlines nanomaterial strategies across three ecological levels (population/community, ecosystem, and cross ...
Chen Hu, Aohan Luan, Yujun Yang, Linlin Wang, Huilin Wang, Ning Wang, Guixin He, Yajie Yang, Rabiya Noor, Jawad Hussain, Longquan Shao   +10 more
wiley   +1 more source