Uropathogenic Escherichia coli P and Type 1 fimbriae act in synergy in a living host to facilitate renal colonization leading to nephron obstruction. [PDF]
The progression of a natural bacterial infection is a dynamic process influenced by the physiological characteristics of the target organ. Recent developments in live animal imaging allow for the study of the dynamic microbe-host interplay in real-time ...
Keira Melican +6 more
doaj +1 more source
Regulation of poly-GlcNAc expression and fimbriation in uropathogenic "E. coli" [PDF]
The transition of planktonic to sessile lifestyles in bacteria rests upon a tightly controlled program that gets triggered by the environmental composition and whose implementation requires multiple feedback controls. Uropathogenic E.
Hosch, Lucie
core +1 more source
Application of MLST and Pilus gene sequence comparisons to investigate the population structures of Actinomyces naeslundii and Actinomyces oris [PDF]
Actinomyces naeslundii and Actinomyces oris are members of the oral biofilm. Their identification using 16S rRNA sequencing is problematic and better achieved by comparison of metG partial sequences. A.
Radford, David R. +54 more
core +1 more source
Bacterial-epithelial contact is a key determinant of host innate immune responses to enteropathogenic and enteroaggregative escherichia coli [PDF]
Background: Enteropathogenic (EPEC) and Enteroaggregative (EAEC) E. coli have similar, but distinct clinical symptoms and modes of pathogenesis. Nevertheless when they infect the gastrointestinal tract, it is thought that their flagellin causes IL-8 ...
Nigel J Klein +27 more
core +1 more source
Fimbriae-mediated initial adherence is the initial and critical step required for enterotoxigenic Escherichia coli (ETEC) infection. Therefore, vaccine candidates have been developed that target these fimbriae and induce specific anti-fimbriae antibodies
Qiangde Duan +8 more
doaj +1 more source
The yqiC gene of Salmonella enterica serovar Typhimurium (S. Typhimurium) regulates bacterial growth at different temperatures and mice survival after infection. However, the role of yqiC in bacterial colonization and host immunity remains unknown.
Ke-Chuan Wang +10 more
doaj +1 more source
Bacterial Fimbriae Stimulate Proinflammatory Activation in the Endothelium through Distinct TLRs [PDF]
Abstract The major and minor fimbriae proteins produced by the human pathogen Porphyromonas gingivalis are required for invasion of human aortic endothelial cells and for the stimulation of potent inflammatory responses. In this study, we report that native forms of both the major and minor fimbriae proteins bind to and signal through ...
Michael, Davey +8 more
openaire +2 more sources
Antimicrobial surfaces based on self-assembled nanoreactors : from block copolymer synthesis to bacterial adhesion study [PDF]
The aim of this work is to develop a new strategy for the prevention of biofilm growth. For this purpose, we prepared bioactive surfaces resulting from the surface-immobilization of nanoreactors self-assembled from amphiphilic poly(isobutylene)-block ...
Cottenye, Nicolas
core +1 more source
Fimbriae assisted bacterial surface display of heterologous peptides
The display of peptide segments on the surface of bacteria offers many new and exciting applications in biotechnology and medical research. Fimbria-assisted display of heterologous sequences is a paradigm for chimeric organelle display on bacteria. Fimbriae are particularly attractive candidates for epitope display for several reasons: (1) they are ...
Klemm, P., Schembri, M.A.
openaire +4 more sources
Type 3 Fimbriae Encoded on Plasmids Are Expressed from a Unique Promoter without Affecting Host Motility, Facilitating an Exceptional Phenotype That Enhances Conjugal Plasmid Transfer. [PDF]
Horizontal gene transfer (HGT), the transmission of genetic material to a recipient that is not the progeny of the donor, is fundamental in bacterial evolution.
Jonas Stenløkke Madsen +6 more
doaj +1 more source

