Results 21 to 30 of about 31,980 (224)

Diversity in Genetic Regulation of Bacterial Fimbriae Assembled by the Chaperone Usher Pathway

International Journal of Molecular Sciences, 2022
Bacteria express different types of hair-like proteinaceous appendages on their cell surface known as pili or fimbriae. These filamentous structures are primarily involved in the adherence of bacteria to both abiotic and biotic surfaces for biofilm formation and/or virulence of non-pathogenic and pathogenic bacteria.
Dharmender K. Gahlot, Nayyer Taheri, Sheila MacIntyre   +2 more
openaire   +4 more sources

Comparative proteomics of uropathogenic Escherichia coli during growth in human urine identify UCA-like (UCL) fimbriae as an adherence factor involved in biofilm formation and binding to uroepithelial cells [PDF]

, 2015
Uropathogenic Escherichia coli (UPEC) are the primary cause of urinary tract infection (UTI) in humans. For the successful colonisation of the human urinary tract, UPEC employ a diverse collection of secreted or surface-exposed virulence factors ...
Allsopp, LP, Moriel, DG, Schembri, MA, Totsika, M, Webb, RI, Wurpel, DJ   +5 more
core   +1 more source

Electron Transport Chain Is Biochemically Linked to Pilus Assembly Required for Polymicrobial Interactions and Biofilm Formation in the Gram-Positive Actinobacterium Actinomyces oris. [PDF]

, 2017
The Gram-positive actinobacteria Actinomyces spp. are key colonizers in the development of oral biofilms due to the inherent ability of Actinomyces to adhere to receptor polysaccharides on the surface of oral streptococci and host cells.
Belkys C. Sanchez, Bryan Tran, Chenggang Wu, Chungyu Chang, Hung Ton-That, Indranil Biswas   +5 more
core   +2 more sources

A multivalent vaccine candidate targeting enterotoxigenic Escherichia coli fimbriae for broadly protecting against porcine post-weaning diarrhea

Veterinary Research, 2020
Fimbriae-mediated initial adherence is the initial and critical step required for enterotoxigenic Escherichia coli (ETEC) infection. Therefore, vaccine candidates have been developed that target these fimbriae and induce specific anti-fimbriae antibodies
Qiangde Duan, Shengmei Pang, Wenwen Wu, Boyu Jiang, Weiping Zhang, Siguo Liu, Xiaojun Wang, Zhiming Pan, Guoqiang Zhu   +8 more
doaj   +1 more source

Highly conserved type 1 pili promote enterotoxigenic E. coli pathogen-host interactions [PDF]

, 2017
Enterotoxigenic Escherichia coli (ETEC), defined by their elaboration of heat-labile (LT) and/or heat-stable (ST) enterotoxins, are a common cause of diarrheal illness in developing countries.
Begum, Yasmin Ara, Ciorba, Matthew A, Fleckenstein, James M, Hultgren, Scott J, Kuhlman, F. Matthew, Qadri, Firdausi, Rashu, Rasheduzzaman, Sheikh, Alaullah   +7 more
core   +3 more sources

P-fimbriae, bacterial adhesion, and pyelonephritis. [PDF]

Archives of Disease in Childhood, 1984
L'aptitude des agents pathogenes a adherer aux membranes muqueuses est maintenant reconnue comme un facteur potentiel de virulence; elle est souvent en rapport avec la presence de filaments proteiniques capables de reconnaitre des recepteurs, souvent glucidiques sur les membranes des cellules epitheliales.
openaire   +2 more sources

Discovery of Bacterial Fimbria–Glycan Interactions Using Whole-Cell Recombinant Escherichia coli Expression

mBio, 2021
Understanding the tropism of pathogens for host and tissue requires a complete understanding of the host receptors targeted by fimbrial adhesins. Furthermore, blocking adhesion is a promising strategy to counter increasing antibiotic resistance and is enabled by the identification of host receptors.
Christopher J. Day, Alvin W. Lo, Lauren E. Hartley-Tassell, M. Pilar Argente, Jessica Poole, Nathan P. King, Joe Tiralongo, Michael P. Jennings, Mark A. Schembri   +8 more
openaire   +4 more sources

Role of yqiC in the pathogenicity of Salmonella and innate immune responses of human intestinal epithelium

Frontiers in Microbiology, 2016
The yqiC gene of Salmonella enterica serovar Typhimurium (S. Typhimurium) regulates bacterial growth at different temperatures and mice survival after infection. However, the role of yqiC in bacterial colonization and host immunity remains unknown.
Ke-Chuan Wang, Ke-Chuan Wang, Chih-Hung Huang, Shih-Min Din, Ching-Kuo Chen, Hsu-Wei Fang, Hsu-Wei Fang, Ming-Te Huang, Ming-Te Huang, Shiuh-Bin Fang, Shiuh-Bin Fang   +10 more
doaj   +1 more source

The long polar fimbriae (lpf) operon and its flanking regions in bovine Escherichia coli O157:H43 and STEC O136:H12 strains [PDF]

, 2013
Long polar fimbriae (Lpf) are intestinal adhesins and important virulence factors of pathogenic Escherichia coli strains. We cloned and sequenced the lpf2-1 operon (lpf2ABCD) and its flanking regions of an intimin- and Shiga toxin-negative E.
Dobrindt, Ulrich, Galli, Lucia, Horváth, Balázs, Maróti, Gergely, Rivas, Marta, Sváb, Domonkos, Torres, Alfredo, Tóth, István   +7 more
core   +1 more source

Fimbriae assisted bacterial surface display of heterologous peptides

International Journal of Medical Microbiology, 2000
The display of peptide segments on the surface of bacteria offers many new and exciting applications in biotechnology and medical research. Fimbria-assisted display of heterologous sequences is a paradigm for chimeric organelle display on bacteria. Fimbriae are particularly attractive candidates for epitope display for several reasons: (1) they are ...
Klemm, P., Schembri, M.A.
openaire   +2 more sources