Journal of Oral Microbiology, 2023 Background Mfa1 fimbriae of the periodontal pathogen Porphyromonas gingivalis are responsible for biofilm formation and comprise five proteins: Mfa1–5. Two major genotypes, mfa170 and mfa153, encode major fimbrillin.
Miyuna Fujimoto +7 more
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Aggregative adherence fimbriae form compact structures as seen by SAXS [PDF]
Scientific Reports, 2023 Bacterial colonization is mediated by fimbriae, which are thin hair-like appendages dispersed from the bacterial surface. The aggregative adherence fimbriae from enteroaggregative E. coli are secreted through the outer membrane and consist of polymerized
Rie Jønsson +8 more
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Fimbriae potentiate Aggregatibacter actinomycetemcomitans for periodontal disease [PDF]
Current Research in Microbial SciencesAggregatibacter actinomycetemcomitans is a major contributor to aggressive periodontitis and has been increasingly implicated in systemic conditions, such as rheumatoid arthritis and Alzheimer’s disease.
Yanyan Fu +2 more
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Mfa4, an Accessory Protein of Mfa1 Fimbriae, Modulates Fimbrial Biogenesis, Cell Auto-Aggregation, and Biofilm Formation in Porphyromonas gingivalis. [PDF]
PLoS ONE, 2015 Porphyromonas gingivalis, a gram-negative obligate anaerobic bacterium, is considered to be a key pathogen in periodontal disease. The bacterium expresses Mfa1 fimbriae, which are composed of polymers of Mfa1.
Ryota Ikai +8 more
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Macrophage activation and invasion by P. gingivalis is modulated by PPAD and accessory fimbriae subunits [PDF]
Journal of Oral MicrobiologyBackground Porphyromonas gingivalis is a master manipulator of host immune responses in the periodontium. Peptidyl arginine deiminase (PPAD), a recently identified virulence factor of P.
Aleksandra Wielento +10 more
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PapB Family Regulators as Master Switches of Fimbrial Expression [PDF]
MicroorganismsSome bacterial species within the Enterobacteriaceae family possess different types of fimbrial (pili) adhesins that promote adherence to cells and colonization of host tissues.
Fariba Akrami +3 more
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CRP-Cyclic AMP Regulates the Expression of Type 3 Fimbriae via Cyclic di-GMP in Klebsiella pneumoniae. [PDF]
PLoS ONE, 2016 Klebsiella pneumoniae is the predominant pathogen isolated from liver abscesses of diabetic patients in Asian countries. However, the effects of elevated blood glucose levels on the virulence of this pathogen remain largely unknown.
Ching-Ting Lin +5 more
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Host range and zoonotic potential linked to P-like fimbrial (PLF) adhesin specificity in avian pathogenic Escherichia coli. [PDF]
PLoS PathogensFimbrial adhesins are surface-associated bacterial proteins that contribute to colonization, tissue tropism, and biofilm formation. Genomic analysis of the avian pathogenic Escherichia coli (APEC) strain QT598 identified a plasmid-localized fimbrial ...
Fariba Akrami +5 more
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Japanese Dental Science Review, 2021 In general, the periodontal pathogen Porphyromonas gingivalis expresses distinct FimA and Mfa1 fimbriae. Each of these consists of five FimA–E and five Mfa1–5 proteins encoded by the fim and mfa gene clusters, respectively.
Yoshiaki Hasegawa, Keiji Nagano
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In Silico Destruction of Porphyromonas gingivalis Fimbriae by Streptomyces sp. Strain GMY02 [PDF]
BIO Web of Conferences, 2023 Porphyromonas gingivalis, a keystone pathogen in chronic periodontitis, has fimbria as one of the most important virulence factors because it plays a vital role in the pathogenesis of P. gingivalis infection.
Kusuma Djati Fanni +6 more
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