Results 31 to 40 of about 16,369 (183)

TLR2 Activation by Porphyromonas gingivalis Requires Both PPAD Activity and Fimbriae

Frontiers in Immunology, 2022
Porphyromonas gingivalis, a keystone oral pathogen implicated in development and progression of periodontitis, may also contribute to the pathogenicity of diseases such as arthritis, atherosclerosis, and Alzheimer’s. P. gingivalis is a master manipulator
Aleksandra Wielento, Grzegorz P. Bereta, Katarzyna B. Łagosz-Ćwik, Sigrun Eick, Richard J. Lamont, Aleksander M. Grabiec, Jan Potempa, Jan Potempa   +7 more
doaj   +1 more source

The Multifunctional Protein YdiV Represses P Fimbria-Mediated Adherence in Uropathogenic Escherichia coli [PDF]

Journal of Bacteriology, 2013
YdiV, a degenerate EAL domain protein, represses motility by interacting with FlhD to abolish FlhDC interaction with DNA. Here, we demonstrate that deletion of ydiV dysregulates coordinate control of motility and adherence by increasing adherence of Escherichia coli CFT073 to a bladder epithelial cell line by specifically increasing production of P ...
Rachel R, Spurbeck, Christopher J, Alteri, Stephanie D, Himpsl, Harry L T, Mobley   +3 more
openaire   +2 more sources

Protein translation and cell death: the role of rare tRNAs in biofilm formation and in activating dormant phage killer genes. [PDF]

PLoS ONE, 2008
We discovered previously that the small Escherichia coli proteins Hha (hemolysin expression modulating protein) and the adjacent, poorly-characterized YbaJ are important for biofilm formation; however, their roles have been nebulous.
Rodolfo García-Contreras, Xue-Song Zhang, Younghoon Kim, Thomas K Wood   +3 more
doaj   +1 more source

The PapB/FocB family protein TosR acts as a positive regulator of flagellar expression and is required for optimal virulence of uropathogenic Escherichia coli

Frontiers in Microbiology, 2023
Uropathogenic Escherichia coli (UPEC) is a major causative agent of urinary tract infections. The bacteria internalize into the uroepithelial cells, where aggregate and form microcolonies.
Hidetada Hirakawa, Mizuki Shimokawa, Koshi Noguchi, Minori Tago, Hiroshi Matsuda, Ayako Takita, Kazutomo Suzue, Hirotaka Tajima, Ikuro Kawagishi, Haruyoshi Tomita, Haruyoshi Tomita   +10 more
doaj   +1 more source

Synthesis of a Putative Antigenic Heptapeptide from Escherichia Coli K88 ab Protein Fimbriae. [PDF]

Acta Chemica Scandinavica, 1986
The heptapeptide Tyr-Arg-Glu-Asp-Met-Glu-Tyr-OMe, spanning region 213-219 of Escherichia coli K88 ab protein fimbriae, was synthesized with an overall yield of 37% using dicyclohexylcarbodiimide (DCC) and 1-hydroxybenzotriazole (HOBt) preactivation in all condensation reactions. The C-terminal was protected as the methyl ester. The protection scheme of
Morten Meldal, Alexander Senning, Rita Grønbæk Hazell, Henning Lund, Povl Krogsgaard-Larsen, Ragnar Ryhage, Roland Isaksson   +6 more
openaire   +2 more sources

IscR Regulation of Type 3 Fimbriae Expression in Klebsiella pneumoniae CG43

Frontiers in Microbiology, 2017
In Klebsiella pneumoniae, we have previously shown that IscR, an Fe–S cluster-containing transcriptional factor, plays a dual role in controlling capsular polysaccharide biosynthesis and iron-acquisition systems by switching between its holo and apo ...
Tien-Huang Lin, Tien-Huang Lin, Cheng-Yin Tseng, Cheng-Yin Tseng, Yi-Chyi Lai, Chien-Chen Wu, Chun-Fa Huang, Chun-Fa Huang, Ching-Ting Lin, Ching-Ting Lin   +9 more
doaj   +1 more source

The Effects of Escherichia coli S-Fimbriae and Outer Membrane Protein A on Rat Pial Arterioles [PDF]

Pediatric Research, 1996
Cerebral vascular injury is common in bacterial meningitis, but the role of microbial factors associated with this phenomenon is unclear. Escherichia coli S-fimbriae and outer membrane protein A (OmpA) have been shown to promote binding and invasion of E. coli to brain microvascular endothelial cells, respectively.
A M, Garner, K S, Kim
openaire   +2 more sources

Role of SefA subunit protein of SEF14 fimbriae in the pathogenesis of Salmonella enterica serovar Enteritidis [PDF]

Infection and Immunity, 1997
In this study, the role of the SefA subunit protein of SEF14 fimbriae in the pathogenesis of Salmonella enterica serovar Enteritidis was investigated. This was accomplished by mutating the sefA gene in the chromosome of two strains of S. enterica serovar Enteritidis by allelic exchange with a copy that has been inactivated by interruption with a ...
Ogunniyi, A., Kotlarski, I., Morona, R., Manning, P.   +3 more
openaire   +2 more sources

H-NS is the major repressor of Salmonella Typhimurium Pef fimbriae expression

Virulence, 2019
Fimbriae play an important role in adhesion and are therefore essential for the interaction of bacteria with the environments they encounter. Most of them are expressed in vivo but not in vitro, thus making difficult the full characterization of these ...
Genaro Alejandro Hurtado-Escobar, Olivier Grépinet, Pierre Raymond, Nadia Abed, Philippe Velge, Isabelle Virlogeux-Payant   +5 more
doaj   +1 more source

The Relationship between Mutations in Gene-Specific Domains of Salivary Fibronectin (cFn) and Dynamin-2 (Dynm-2) and the Development of Porphyromonas gingivalis-Initiated Periodontitis

Journal of Molecular Pathology, 2022
Periodontitis is a chronic inflammatory disease characterized by the destruction of the supporting structures of the teeth. Its high prevalence and negative effects on quality of life make it one of the current problems in dentistry.
Elena A. Oleinik, Anna V. Goncharenko
doaj   +1 more source