Results 11 to 20 of about 16,814 (210)

TLR2 Activation by Porphyromonas gingivalis Requires Both PPAD Activity and Fimbriae [PDF]

Frontiers in Immunology, 2022
Porphyromonas gingivalis, a keystone oral pathogen implicated in development and progression of periodontitis, may also contribute to the pathogenicity of diseases such as arthritis, atherosclerosis, and Alzheimer’s. P. gingivalis is a master manipulator
Aleksandra Wielento, Grzegorz P. Bereta, Katarzyna B. Łagosz-Ćwik, Sigrun Eick, Richard J. Lamont, Aleksander M. Grabiec, Jan Potempa, Jan Potempa   +7 more
doaj   +2 more sources

H-NS is the major repressor of Salmonella Typhimurium Pef fimbriae expression

Virulence, 2019
Fimbriae play an important role in adhesion and are therefore essential for the interaction of bacteria with the environments they encounter. Most of them are expressed in vivo but not in vitro, thus making difficult the full characterization of these ...
Genaro Alejandro Hurtado-Escobar, Olivier Grépinet, Pierre Raymond, Nadia Abed, Philippe Velge, Isabelle Virlogeux-Payant   +5 more
doaj   +2 more sources

Structural and functional studies of Porphyromonas gingivalis fimbrial proteins

Journal of Oral Microbiology, 2017
Porphyromonas gingivalis expresses two forms of fimbriae, FimA and Mfa1. Each fimbria consists of five proteins; FimA-E and Mfa1-5. While the assembly of the type-1 fimbriae from Escherichia coli is well studied; the chaperone-usher pathway, very little ...
Karina Persson, Michael Hall
doaj   +2 more sources

Secretion of type-1-fimbriae binding proteins from human neutrophil granulocytes

Inflammation, 1996
Granule matrix proteins secreted from human neutrophils after ionomycin stimulation were separated by SDS-PAGE, blotted onto a polyvinylidene diflouride (PVDF) membrane and overlaid with the mannose-binding lectin concanavalin A (Con A) or Escherichia coli bacteria exposing type-I-fimbriae.
A, Karlsson, C, Dahlgren
openaire   +3 more sources

Long Polar Fimbriae of Enterohemorrhagic Escherichia coli O157:H7 Bind to Extracellular Matrix Proteins [PDF]

Infection and Immunity, 2011
ABSTRACT Adherence to intestinal cells is a key process in infection caused by enterohemorrhagic Escherichia coli (EHEC). Several adhesion factors that mediate the binding of EHEC to intestinal cells have been described, but the receptors involved in their recognition are not fully characterized ...
Farfan, Mauricio J., Cantero, Lidia, Vidal, Roberto, Botkin, Douglas J., Torres, Alfredo G.   +4 more
openaire   +5 more sources

IscR Regulation of Type 3 Fimbriae Expression in Klebsiella pneumoniae CG43

Frontiers in Microbiology, 2017
In Klebsiella pneumoniae, we have previously shown that IscR, an Fe–S cluster-containing transcriptional factor, plays a dual role in controlling capsular polysaccharide biosynthesis and iron-acquisition systems by switching between its holo and apo ...
Tien-Huang Lin, Tien-Huang Lin, Cheng-Yin Tseng, Cheng-Yin Tseng, Yi-Chyi Lai, Chien-Chen Wu, Chun-Fa Huang, Chun-Fa Huang, Ching-Ting Lin, Ching-Ting Lin   +9 more
doaj   +2 more sources

Sequence analyses of fimbriae subunit FimA proteins on Actinomyces naeslundii genospecies 1 and 2 and Actinomyces odontolyticus with variant carbohydrate binding specificities

BMC Microbiology, 2006
Background Actinomyces naeslundii genospecies 1 and 2 express type-2 fimbriae (FimA subunit polymers) with variant Galβ binding specificities and Actinomyces odontolyticus a sialic acid specificity to colonize different oral surfaces.
Persson Karina, Birve Anna, Öhman Ulla, Hallberg Kristina, Drobni Mirva, Johansson Ingegerd, Strömberg Nicklas   +6 more
doaj   +2 more sources

Subversion of a family of antimicrobial proteins by Salmonella enterica [PDF]

Frontiers in Cellular and Infection Microbiology
Salmonella enterica is a food-borne pathogen able to cause a wide spectrum of diseases ranging from mild gastroenteritis to systemic infections. During almost all stages of the infection process Salmonella is likely to be exposed to a wide variety of ...
Roman G. Gerlach, Roman G. Gerlach, Irene Wittmann, Lena Heinrich, Olaf Pinkenburg, Torben Meyer, Laura Elpers, Christiane Schmidt, Michael Hensel, Markus Schnare   +9 more
doaj   +3 more sources

Protection Against Pneumonia Induced by Vaccination with Fimbriae Subunits from Klebsiella pneumoniae

Vaccines
Background: Klebsiella pneumoniae infections pose a great burden worldwide, causing high morbidity and mortality, which are worsened by the increase in multidrug-resistant strains.
Lucas Assoni, Isabelle Ciaparin, Monalisa Martins Trentini, Juliana Baboghlian, Gabriel Rodrigo, Brenda Vieira Ferreira, José Aires Pereira, Carlos Martinez, Lucio Ferraz, Raquel Girardello, Lucas Miguel Carvalho, Anders P. Hakansson, Thiago Rojas Converso, Michelle Darrieux   +13 more
doaj   +2 more sources

Mechanism of pathogen‐specific TLR4 activation in the mucosa: Fimbriae, recognition receptors and adaptor protein selection

European Journal of Immunology, 2006
AbstractThe mucosal host defence discriminates pathogens from commensals, and prevents infection while allowing the normal flora to persist. Paradoxically, Toll‐like receptors (TLR) control the mucosal defence against pathogens, even though the TLR recognise conserved molecules like LPS, which are shared between pathogens and commensals.
Hans, Fischer, Masahiro, Yamamoto, Shizuo, Akira, Bruce, Beutler, Catharina, Svanborg   +4 more
openaire   +3 more sources