Results 91 to 100 of about 11,062 (165)

Inner-membrane protein MorC is involved in fimbriae production and biofilm formation in Aggregatibacter actinomycetemcomitans

Microbiology, 2016
Fimbrial subunit synthesis, secretion and assembly on the surface of the periodontal pathogen Aggregatibacter actinomycetemcomitans are essential for biofilm formation. A recent quantitative proteomics study employing an afimbriated strain and a developed mutant isogenic for the inner-membrane protein morphogenesis protein C (MorC) revealed that the ...
Kenneth P, Smith, Teresa, Ruiz, Keith P, Mintz   +2 more
openaire   +2 more sources

Colony Immunoblotting Assay for Detection of Bacterial Cell-surface or Extracellular Proteins

Bio-Protocol, 2013
This simple protocol describes how to detect antigens from agar-grown bacterial colonies transferred to nitrocellulose using specific antibodies. The protocol is well suitable for detection of bacterial proteins exposed on the cell surface or secreted to
Timo Lehti, Benita Westerlund-Wikström
doaj   +1 more source

Constraints on lateral gene transfer in promoting fimbrial usher protein diversity and function [PDF]

Open Biology, 2017
Fimbriae are long, adhesive structures widespread throughout members of the family Enterobacteriaceae. They are multimeric extrusions, which are moved out of the bacterial cell through an integral outer membrane protein called usher.
Christopher J. Stubenrauch, Gordon Dougan, Trevor Lithgow, Eva Heinz   +3 more
doaj   +1 more source

Pharmacologic MRI Brain Imaging Studies of Serotonin 5‐HT1 Receptor Agonists in Awake Mice

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Serotonin (5‐hydroxytryptamine, 5‐HT) type‐1 G protein‐coupled receptors are expressed throughout the central nervous system. 5‐HT1AR activation is the putative mechanism of approved drugs for generalized anxiety disorder and major depressive disorder and is being studied in the treatment of autism and neurological disorders.
Brittany M. Brems, Erin E. Sullivan, Ryan P. McGlynn, Praveen Kulkarni, Craig F. Ferris, Raymond G. Booth   +5 more
wiley   +1 more source

Random Mutagenesis in Porphyromonas gingivalis Enables Isolation of Mutants With Enhanced Secreted Protease Activity

Molecular Oral Microbiology, Volume 41, Issue 3, Page 158-164, June 2026.
ABSTRACT Porphyromonas gingivalis is a key pathogen in periodontitis, with secreted proteases as major virulence factors. We developed a screening method to generate and identify P. gingivalis mutants with elevated protease activity. Mutations were induced using the mutagens 2,6‐diaminopurine (2,6‐DAP) or ethyl methanesulfonate (EMS), and the ...
Takeru Nakabayashi, Satoshi Yuhara, Kosei Tanaka   +2 more
wiley   +1 more source

Binding of lactoferrin and free secretory component to enterotoxigenic Escherichia coli [PDF]

, 2001
The ability of two glycoproteins of human milk, lactoferrin and free secretory component, to bind to Escherichia coli colonization factors (CFAs) was investigated using immunocytochemistry assays of enriched fimbrial extracts.
Andréa Nascimento Araújo, Appelmelk, Ashkenazi, Bradford, Brock, Buts, Bühler, Cravioto, Cravioto, Dallas, Erdei, Evans, Evans, Falk, Faruque, Giugliano, Glass, Guth, Inaiara Rosa Oliveira, Kobayashi, Kovar, Laemmli, Loreny Gimenes Giugliano, Mestecky, Mynott, Naidu, Paniagua, Reis, Smyth, Sonia Nair Bao, Towbin, Young   +31 more
core   +1 more source

Micro‐Stimulation Timing Framed Around an Averaged Theta Period of Stimulation Determines Hippocampal Recruitment in Cued Fear Conditioning

Hippocampus, Volume 36, Issue 3, May 2026.
ABSTRACT The importance of precise timing of neuronal activity, relative to ongoing slower oscillations, is reshaping the engram theory and our understanding of how memories are encoded and stored. The hippocampal theta‐wave phase‐encoding of neuronal firing predicts behavioral outcomes and cognitive performance in memory tasks.
Paula Gonçalves Vieira Teixeira, Leonardo de Oliveira Guarnieri, Grace Schenatto Pereira, Márcio Flávio Dutra Moraes   +3 more
wiley   +1 more source

Role of SefA subunit protein of SEF14 fimbriae in the pathogenesis of Salmonella enterica serovar Enteritidis [PDF]

Infection and Immunity, 1997
In this study, the role of the SefA subunit protein of SEF14 fimbriae in the pathogenesis of Salmonella enterica serovar Enteritidis was investigated. This was accomplished by mutating the sefA gene in the chromosome of two strains of S. enterica serovar Enteritidis by allelic exchange with a copy that has been inactivated by interruption with a ...
Ogunniyi, A., Kotlarski, I., Morona, R., Manning, P.   +3 more
openaire   +2 more sources

Trueperella pyogenes–Associated Acute Pneumonia in Korean Native Calves

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Trueperella pyogenes can cause a wide range of suppurative infections, including urogenital and mammary infections, liver abscesses and pneumonia. This case report demonstrates Trueperella pyogenes as a primary cause of bovine respiratory disease in Korean native calves.
Min‐Jeong Ji, Youngjun Kim, Byoung‐Soo Kim, Jongho Kim, Kyoung‐Seong Choi   +4 more
wiley   +1 more source

Macrophage activation and invasion by P. gingivalis is modulated by PPAD and accessory fimbriae subunits

Journal of Oral Microbiology
Background Porphyromonas gingivalis is a master manipulator of host immune responses in the periodontium. Peptidyl arginine deiminase (PPAD), a recently identified virulence factor of P.
Aleksandra Wielento, Dominika M. Drapała, Marina Terekhova, Anna Jacuła, Maxim N. Artyomov, Jakub Kochan, Yoshiaki Hasegawa, Danuta Mizgalska, Juhi Bagaitkar, Aleksander M. Grabiec, Jan Potempa   +10 more
doaj   +1 more source