Results 91 to 100 of about 16,369 (183)

Human Stem Cell Transplantation, Immunosuppression, and Noninvasive In vivo Cell Tracking in the Mouse Brain

Current Protocols, Volume 6, Issue 8, August 2026.
Abstract Stem cell therapies have emerged as potential therapeutics of interest for many central nervous system diseases, including stroke, epilepsy, neurodegenerative diseases, and traumatic brain injury. Preclinical models are required to evaluate the migration of transplanted stem cells to various areas of the brain, monitor graft survival to ...
Kevin S. Chen, Kyle J. Loi, Lisa M. McGinley, Osama N. Kashlan, Diana M. Rigan, Shayna N. Mason, Jacquelin F. Kwentus, Andrew D. Carter, Masha G. Savelieff, Eva L. Feldman   +9 more
wiley   +1 more source

Deciphering the Function and Structure of PA1216 as an S‐Adenosyl‐l‐Methionine Binding Protein Using Differential Scanning Fluorimetry and Circular Dichroism

Protein Science, Volume 35, Issue 8, August 2026.
Abstract Microbes produce bioactive secondary metabolites as toxins, pigments, or virulence factors. These specialized compounds are produced by nonribosomal peptide synthetases (NRPS), polyketide synthases (PKS), or hybrid NRPS/PKS pathways. The genes encoding NRPS and PKS reside in biosynthetic gene clusters (BGCs), some of which have no identified ...
Amaan M. Fruitwala, Jade X. Tiszler, Daniel Watson, Mansi Sinha, Tony D. Davis   +4 more
wiley   +1 more source

S-layers at second glance? Altiarchaeal grappling hooks (hami) resemble archaeal S-layer proteins in structure and sequence

Frontiers in Microbiology, 2015
The uncultivated Ca. Altiarchaeum hamiconexum (formerly known as SM1 Euryarchaeon) carries highly specialized nano-grappling hooks (hami) on its cell surface. Until now little is known about the major protein forming these structured fibrous cell surface
Alexandra Kristin Perras, Alexandra Kristin Perras, Bertram eDaum, Christine eZiegler, Lynelle eTakahashi, Musahid eAhmed, Gerhard eWanner, Andreas eKlingl, Gerd eLeitinger, Dagmar eKolb-Lenz, Simonetta eGribaldo, Anna eAuerbach, Maximilian eMora, Maximilian eMora, Alexander Josef Probst, Annett eBellack, Christine eMoissl-Eichinger, Christine eMoissl-Eichinger, Christine eMoissl-Eichinger   +18 more
doaj   +1 more source

Nanostructured Ti–6Al–4V Reduces Adhesion of Several Bacterial Species: An In Vitro Study

Small Science, Volume 6, Issue 8, August 2026.
Alkaline etching transforms Ti–6Al–4V into nanostructured, highly hydrophilic surfaces with thicker oxide layers and selective alloy depletion. These physicochemical changes reduce early bacterial adhesion across multiple species by limiting effective nanoscale contact points, while osteoblast‐like cells retain good attachment and spreading.
Sadaf Khalatbarizamanpoor, Adrian G. Nowotnick, Stephanie Lippmann, Antje Häder, Felix Otto, Lena Raupach, Torsten Fritz, Yasmina Reisser, Jörg Bossert, Bettina Löffler, Klaus D. Jandt   +10 more
wiley   +1 more source

[Rapid purification of Bordetella pertussis fimbria 2, 3 proteins and their immunogenicities].

Mikrobiyoloji bulteni, 2007
Bordetella pertussis fimbria antigens play an important role in the adhesion to the cell surfaces, and induce the formation of protective antibodies in the host. The aim of this study was to purify the fimbria proteins by a rapid and easy method which involved Superdex 75 gel filtration chromatography, and to investigate their immunogenicity.
Ptnar, Atakan Ablay, Erkan, Ozcengiz
openaire   +1 more source

Pre‐Clinical Development of Two DNA Vaccines Encoding MrkA of Klebsiella pneumoniae: Effect of Plasmid Backbone on Immunogenicity and Protective Efficacy Against Sepsis

Microbial Biotechnology, Volume 19, Issue 8, August 2026.
Pre‐clinical development of two DNA vaccines encoding the MrkA fimbrial subunit of Klebsiella pneumoniae using different plasmid backbones: pVAX1 (commercial) and PLASMIVAX (with additional CpG motifs). Both DNA vaccine candidates expressed the antigen in eukaryotic cells but differed in their immunogenicity and protective efficacy against sepsis in ...
Marta Vicente‐Pazos, Estéfani García‐Ríos, Laura Quílez‐Agraz, Gal·la Ustrell‐Sallent, Pilar Pérez‐Romero, Mireia López‐Siles, Michael J. McConnell   +6 more
wiley   +1 more source

Unveiling a Novel Mechanism of Enhanced Secretion, Cargo Loading, and Accelerated Dynamics of Bacterial Extracellular Vesicles Following Antibiotic Exposure

Journal of Extracellular Vesicles
Antibiotic exposure substantially alters the production mechanisms of bacterial extracellular vesicles (BEVs), which serve as carriers for intercellular exchange of DNA, proteins, and nutrients, yet the underlying mechanisms remain elusive.
Jinpeng Li, Chao Li, Yun Han, Yulian Hu, Jian Yang, Heting Xu, Xinggui Chen, Ming Yang, Jing Zuo, Yizhi Tang, Changwei Lei, Cui Li, Hongning Wang   +12 more
doaj   +1 more source

Capsular polysaccharide inhibits adhesion of Bifidobacterium longum 105-A to enterocyte-like Caco-2 cells and phagocytosis by macrophages

Gut Pathogens, 2017
Background Bifidobacterium longum 105-A produces markedly high amounts of capsular polysaccharides (CPS) and exopolysaccharides (EPS) that should play distinct roles in bacterial–host interactions. To identify the biological function of B.
Amin Tahoun, Hisayoshi Masutani, Hanem El-Sharkawy, Trudi Gillespie, Ryo P. Honda, Kazuo Kuwata, Mizuho Inagaki, Tomio Yabe, Izumi Nomura, Tohru Suzuki   +9 more
doaj   +1 more source

Porcine milk fat globule membrane proteins that bind to F4ac fimbria of Escherichia coli

The FASEB Journal, 2012
Post‐weaning colibacillosis in pigs is caused by enterotoxigenic Escherichia coli (ETEC) which is often controlled by antibiotic feed supplements with potential risk of generation of antibiotic resistant bacteria.
Predrag Novakovic, Yanyun Huang, Chandrashekhar Charavaryamath, Betty Lockerbie, John Kelly, Matthew E. Loewen, Elemir Simko   +6 more
openaire   +1 more source

Design, Construction, Expression and Purification of the Gene Encoding Chimeric Cfae, Cotd Protein, from Enterotoxigenic Escherichia Coli

Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2019
Background and Aim: Enterotoxigenic Escherichia coli (ETEC) is one of the most common bacterial causes of diarrhea deaths among children and travelers in developing countries. The ETEC colonization factors, such as CFA/I and CS2 play an important role in
Pooneh Roghanian, Jafar Amani, Shoreh Zare, Zahra Nour Mohammadi   +3 more
doaj