Results 81 to 90 of about 16,369 (183)

TMEM16A chloride channels in the female reproductive tract and their role in normal and dysfunctional pregnancy and labour

The Journal of Physiology, EarlyView.
Abstract figure legend TMEM16A plays a pivotal role in setting the duration of the action potential plateau in human uterine smooth muscle. An increase in TMEM16A expression in labour underpins a lengthening of the plateau and this provides time for the contraction to become larger and longer, important for timely successful labour.
Helena C. Parkington, Harold A. Coleman, Penelope M. Sheehan, Shaun P. Brennecke, Marianne Tare   +4 more
wiley   +1 more source

Dancing to Another Tune—Adhesive Moonlighting Proteins in Bacteria

Biology, 2014
Biological moonlighting refers to proteins which express more than one function. Moonlighting proteins occur in pathogenic and commensal as well as in Gram-positive and Gram-negative bacteria.
Veera Kainulainen, Timo K. Korhonen
doaj   +1 more source

Phenotypic expression of the gene‐for‐gene interaction in plant pathogenic bacteria: An implication for resistance to bacterial diseases by plants

Agrosystems, Geosciences &Environment, Volume 9, Issue 3, September 2026.
Abstract Plant pathogenic bacteria cause massive losses in agriculture and damage to natural plant habitats. Bacterial pathogens not only reduce crop production, but they also reduce crop quality by releasing toxins into the environment. Pathogenic bacteria that invade plant tissues must overcome the plant's defense mechanisms. Plants possess an innate
Muluken Getahun, Zelalem Bekeko
wiley   +1 more source

MrkH, a novel c-di-GMP-dependent transcriptional activator, controls Klebsiella pneumoniae biofilm formation by regulating type 3 fimbriae expression.

PLoS Pathogens, 2011
Klebsiella pneumoniae causes significant morbidity and mortality worldwide, particularly amongst hospitalized individuals. The principle mechanism for pathogenesis in hospital environments involves the formation of biofilms, primarily on implanted ...
Jonathan J Wilksch, Ji Yang, Abigail Clements, Jacinta L Gabbe, Kirsty R Short, Hanwei Cao, Rosalia Cavaliere, Catherine E James, Cynthia B Whitchurch, Mark A Schembri, Mary L C Chuah, Zhao-Xun Liang, Odilia L Wijburg, Adam W Jenney, Trevor Lithgow, Richard A Strugnell   +15 more
doaj   +1 more source

Identification of Potential Vaccine Strains of Escherichia coli Isolates From Diarrhoeic Calves

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This study aimed to identify vaccine candidate Escherichia coli strains isolated from diarrheic calves. Faecal samples collected from 500 calves were analysed, and E. coli strains were isolated and characterized phenotypically and genotypically. Antibiotic resistance profiles, virulence‐associated genes and MLVA genotyping were used to select 20 ...
Yasemin Erdoğan, Ediz Kağan Özgen, Murat Özmen, Elif Karadeniz Pütür, Nebahat Polat, Ersan Pütür, Mücahit Harmancı, Ercan Atalay, Ahmet Temur, Meryem Güloğlu, Lütfullah Celep, Seyda Cengiz, Mehmet Cemal Adıgüzel, Cihan Öz, Timur Gülhan, Alper Çiftci, Erhan Çiftgül   +16 more
wiley   +1 more source

Reduced diversity and increased virulence-gene carriage in intestinal enterobacteria of coeliac children

BMC Gastroenterology, 2008
Background Coeliac disease is an immune-mediated enteropathology triggered by the ingestion of cereal gluten proteins. This disorder is associated with imbalances in the composition of the gut microbiota that could be involved in its pathogenesis.
Calabuig Miguel, Ribes-Koninckx Carmen, Donat Ester, Sánchez Ester, Nadal Inmaculada, Sanz Yolanda   +5 more
doaj   +1 more source

Characterization of Phylogroups, Virulence Factors and Antimicrobial Resistance in Canine Pyometra‐associated Escherichia coli

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This study characterized 56 Escherichia coli isolates obtained from canine pyometra, which predominantly belonged to phylogroup B2 and harboured multiple virulence genes, with high multidrug resistance rates indicating potential clinical and zoonotic risks. ABSTRACT The presence of multidrug‐resistant extraintestinal pathogenic Escherichia coli (ExPEC)
İnci Başak Müştak, Murat Onur Yazlık, Beyza Nur Şitvan, Hamit Kaan Müştak, Ufuk Kaya   +4 more
wiley   +1 more source

Aberrant ɑSMA expression reveals broad mossy fiber reorganization integrating with tangle and plaque formation and mitoenergetic alteration in the human hippocampus

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Neural network and bioenergetic abnormalities occur with Alzheimer's disease (AD) pathogenesis. METHODS We explored mossy fiber (MF) and mitoenergetic alteration using ɑ‐smooth muscle actin (ɑSMA) and cytochrome c oxidase (COX) immunolabeling in human hippocampus relative to tangle and plaque formation by referring to Braak (0–VI)
Tian Tu, Qi‐Lei Zhang, Zhong‐Ping Sun, Chao Kang, Dan Li, Xin‐Hua Huo, Xiao‐Jie Zhang, Yan Zhang, Mengchao Cui, Aihua Pan, Jian Wang, Xiao‐Xin Yan   +11 more
wiley   +1 more source

Down-Regulation of Flagellar, Fimbriae, and Pili Proteins in Carbapenem-Resistant Klebsiella pneumoniae (NDM-4) Clinical Isolates: A Novel Linkage to Drug Resistance

Frontiers in Microbiology, 2019
The emergence and spread of carbapenem-resistant Klebsiella pneumoniae infections have worsened the current situation worldwide, in which totally drug-resistant strains (bad bugs) are becoming increasingly prominent. Bacterial biofilms enable bacteria to
Divakar Sharma, Anjali Garg, Manish Kumar, Faraz Rashid, Asad U. Khan   +4 more
doaj   +1 more source

Current Advances of Molecular Biomarkers and Liquid Biopsies Techniques in Ovarian Cancer

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Ovarian cancer (OC) remains a lethal gynecological malignancy with challenges in early diagnosis, treatment monitoring, and overcoming drug resistance. Liquid biopsy, a noninvasive approach analyzing tumor‐derived components in bodily fluids, has emerged as a promising tool in OC management.
Jingxia Zhang, Weiyan Shan, Jie Yu, Huan Shi, Qiaoping Xu, Hongkai Shang   +5 more
wiley   +1 more source