Results 81 to 90 of about 16,814 (210)

The Oral‐Gut Axis: Bidirectional Interactions Between Microbiome and Diseases

Journal of Periodontal Research, EarlyView.
This study aims to summarize the mechanisms underlying ectopic colonization of the gut by oral pathobionts and the microbial and host factors that regulate this process. ABSTRACT Increased colonization of typically oral microorganisms is frequently observed in the gut mucosa or lumen of individuals with gastrointestinal disorders, including patients ...
Shinya Ebihara, Nobuhiko Kamada
wiley   +1 more source

Targeting aminopeptidase N, a newly identified receptor for F4ac fimbriae, enhances the intestinal mucosal immune response

, 2012
Enterotoxigenic Escherichia coli (ETEC) are a major cause of diarrhea in human and animal. In piglets, ETEC having F4 fimbriae (F4(+) ETEC) induce severe diarrhea, dependent on the presence of receptors for F4 (F4R). In this study, porcine aminopeptidase
Deforce, Dieter, De Geest, Bruno, Melkebeek, V., Rasschaert, K., Tilleman, K, Deforce, D., Melkebeek, Vesna, Favoreel, H., Goddeeris, Bruno, Bellot, P., Cox, Eric, De Geest, B.G., Rasschaert, K, Tilleman, K., Favoreel, Herman, Bellot, Philippe   +15 more
core   +1 more source

Colony Immunoblotting Assay for Detection of Bacterial Cell-surface or Extracellular Proteins

Bio-Protocol, 2013
This simple protocol describes how to detect antigens from agar-grown bacterial colonies transferred to nitrocellulose using specific antibodies. The protocol is well suitable for detection of bacterial proteins exposed on the cell surface or secreted to
Timo Lehti, Benita Westerlund-Wikström
doaj   +1 more source

Constraints on lateral gene transfer in promoting fimbrial usher protein diversity and function [PDF]

Open Biology, 2017
Fimbriae are long, adhesive structures widespread throughout members of the family Enterobacteriaceae. They are multimeric extrusions, which are moved out of the bacterial cell through an integral outer membrane protein called usher.
Christopher J. Stubenrauch, Gordon Dougan, Trevor Lithgow, Eva Heinz   +3 more
doaj   +1 more source

Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang, Geeta Madhuri Bhuvanagiri, Megan Dulkanchainun, Cunyu Wang   +3 more
wiley   +1 more source

Direct evidence that the FimH protein is the mannose-specific adhesin of Escherichia coli type 1 fimbriae [PDF]

Infection and Immunity, 1990
Type 1 fimbriae of Escherichia coli are surface organelles which mediate binding to D-mannose-containing structures. By direct binding of FimH to D-mannose attached to a carrier protein, we demonstrated that this protein was uniquely responsible for the receptor specificity.
K A, Krogfelt, H, Bergmans, P, Klemm
openaire   +2 more sources

TMEM16A chloride channels in the female reproductive tract and their role in normal and dysfunctional pregnancy and labour

The Journal of Physiology, EarlyView.
Abstract figure legend TMEM16A plays a pivotal role in setting the duration of the action potential plateau in human uterine smooth muscle. An increase in TMEM16A expression in labour underpins a lengthening of the plateau and this provides time for the contraction to become larger and longer, important for timely successful labour.
Helena C. Parkington, Harold A. Coleman, Penelope M. Sheehan, Shaun P. Brennecke, Marianne Tare   +4 more
wiley   +1 more source

Diverse Microbial Communities Assemble on Both Recalcitrant and Labile Carbon Sources

Environmental Microbiology, Volume 28, Issue 7, July 2026.
Taxonomically and functionally distinct communities assemble on cellulose and its monomer, glucose. Although single carbon sources were provided, high and comparable diversity was maintained in both environments, supported by extensive cross‐feeding and scavenging. However, glucose supported higher biomass than cellulose and selected generalists, while
Kaumudi H. Prabhakara, Yansong Zhao, Kristian Ullrich, Andrew D. Farr, Paul B. Rainey   +4 more
wiley   +1 more source

Epithelial cell binding of group A streptococci by lipoteichoic acid on fimbriae denuded of M protein. [PDF]

The Journal of experimental medicine, 1976
Group A streptococci were treated with various enzymatic and chemical agents in an attempt to dissociate the type-specific M protein from intact surface "fimbriae." Mild peptic digestion at pH 5.8, which was previously shown to extract serologically active M antigen from intact streptococci had little visible effect on the fimbriae even though ...
E H, Beachey, I, Ofek
openaire   +2 more sources

Coordinate gene regulation by fimbriae-induced signal transduction

, 2001
Fimbriae are thread-like polymers displayed in large amounts on the bacterial surface and used by many pathogens to attach to receptors on host tissue surfaces.
Klemm, P., Schembri, M. A., Schembri, Mark, Klemm, Per   +3 more
core   +1 more source