Results 61 to 70 of about 16,369 (183)

Leucine-Responsive Regulatory Protein Lrp and PapI Homologues Influence Phase Variation of CS31A Fimbriae [PDF]

Journal of Bacteriology, 2014
ABSTRACTCS31A, a K88-related surface antigen specified by theclpoperon, is a member of the type P family of adhesive factors and plays a key role in the establishment of disease caused by septicemic and enterotoxigenicEscherichia colistrains. Its expression is under the control of methylation-dependent transcriptional regulation, for which the leucine ...
Graveline, Richard, Garneau, Philippe, Martin, Christine, Mourez, Michael, Hancock, Mark A., Lavoie, Remi, Harel, Josée   +6 more
openaire   +4 more sources

Evolutionary and Epidemiological Characterization of Multidrug‐Resistant Escherichia coli Isolated From Pangolins in China

Integrative Zoology, EarlyView.
ABSTRACT Malayan pangolin populations have fallen to a critically endangered level, and illegal trafficking of wild pangolins is a global problem. Little is known about antimicrobial‐resistant bacteria (MDRB) harbored by pangolins, although pangolins are frequently consumed as food or used in traditional medicine. In this study, we report for the first
Yawen Wang, Xue Wang, Jianan Zhao, Jun Zeng, Shijia Hu, Fang Ji, Guoying Dong, Hongxuan He, Chengmin Wang   +8 more
wiley   +1 more source

Curli of Uropathogenic Escherichia coli Enhance Urinary Tract Colonization as a Fitness Factor

Frontiers in Microbiology, 2019
Curli, a type of fimbriae widely distributed in uropathogenic Escherichia coli (UPEC), are involved in adhesion to human bladder cell surfaces and biofilm development. The role of UPEC curli was evaluated in a murine model of urinary tract infection. The
Víctor M. Luna-Pineda, Leticia Moreno-Fierros, Vicenta Cázares-Domínguez, Damaris Ilhuicatzi-Alvarado, Sara A. Ochoa, Ariadnna Cruz-Córdova, Pedro Valencia-Mayoral, Alejandra Rodríguez-Leviz, Juan Xicohtencatl-Cortes   +8 more
doaj   +1 more source

Orchestrated molecular changes of proliferative, migratory‐fibrillar, synaptic, and postmigratory compartments align with precocious cortex‐type specification in the early human pallium

Journal of Anatomy, EarlyView.
Early human cortical development is organized by transient cellular compartments that define cortical types before mature layers form. Analysis of the human fetal pallium (7.5–15 PCW) shows distinct spatiotemporal trajectories for the archicortex, mesocortex, and neocortex, with delayed but accelerated differentiation in allocortical regions.
Janja Kopić, Fran Božić, Alisa Junaković Munjas, Željka Krsnik, Ivica Kostović   +4 more
wiley   +1 more source

Maturation of fimbria precursor protein by exogenous gingipains inPorphyromonas gingivalisgingipain-null mutant [PDF]

FEMS Microbiology Letters, 2007
Porphyromonas gingivalis expresses several virulence factors such as fimbriae and proteases, termed gingipains, which are enzymes that process precursor fimbriae proteins. Thus, gingipain-null mutants lack mature fimbriae. Membrane vesicle-depleted supernatants (VDS) containing soluble gingipains were prepared as an exogenous gingipain fraction ...
Takahiro, Kato, Tetsuhisa, Tsuda, Hiroko, Omori, Takafumi, Kato, Tamotsu, Yoshimori, Atsuo, Amano   +5 more
openaire   +2 more sources

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Protection Against Pneumonia Induced by Vaccination with Fimbriae Subunits from Klebsiella pneumoniae

Vaccines
Background: Klebsiella pneumoniae infections pose a great burden worldwide, causing high morbidity and mortality, which are worsened by the increase in multidrug-resistant strains.
Lucas Assoni, Isabelle Ciaparin, Monalisa Martins Trentini, Juliana Baboghlian, Gabriel Rodrigo, Brenda Vieira Ferreira, José Aires Pereira, Carlos Martinez, Lucio Ferraz, Raquel Girardello, Lucas Miguel Carvalho, Anders P. Hakansson, Thiago Rojas Converso, Michelle Darrieux   +13 more
doaj   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Permissive linker insertion sites in the outer membrane protein of 987P fimbriae of Escherichia coli

Journal of Bacteriology, 1994
The FasD protein is essential for the biogenesis of 987P fimbriae of Escherichia coli. In this study, subcellular fractionation was used to demonstrate that FasD is an outer membrane protein. In addition, the accessibility of FasD to proteases established the presence of surface-exposed FasD domains on both sides of the outer membrane.
D M, Schifferli, M A, Alrutz
openaire   +3 more sources

Colony Immunoblotting Assay for Detection of Bacterial Cell-surface or Extracellular Proteins

Bio-Protocol, 2013
This simple protocol describes how to detect antigens from agar-grown bacterial colonies transferred to nitrocellulose using specific antibodies. The protocol is well suitable for detection of bacterial proteins exposed on the cell surface or secreted to
Timo Lehti, Benita Westerlund-Wikström
doaj   +1 more source