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Vaccine, 2001
Haemophilus influenzae type b (Hib) capsular polysaccharide (polyribosylribitol phosphate, PRP) is the active component of conjugate vaccines that have proven successful in preventing invasive Hib disease. Conjugation of PRP to a protein carrier greatly improves its immunogenicity providing protection in infants and subsequent antibody maturation upon ...
Andrew Gorringe
exaly +3 more sources
Haemophilus influenzae type b (Hib) capsular polysaccharide (polyribosylribitol phosphate, PRP) is the active component of conjugate vaccines that have proven successful in preventing invasive Hib disease. Conjugation of PRP to a protein carrier greatly improves its immunogenicity providing protection in infants and subsequent antibody maturation upon ...
Andrew Gorringe
exaly +3 more sources
1991
Fimbriae are important virulence factors in a number of enterobacterial infections. It is generally thought that they increase the pathogenic potential of bacteria by mediating adherence to glycoconjugates of host epithelia, thus giving resistance to mechanical clearance defense systems of the body.
Timo K. Korhonen +10 more
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Fimbriae are important virulence factors in a number of enterobacterial infections. It is generally thought that they increase the pathogenic potential of bacteria by mediating adherence to glycoconjugates of host epithelia, thus giving resistance to mechanical clearance defense systems of the body.
Timo K. Korhonen +10 more
openaire +1 more source
Microbes and Infection, 2005
Porphyromonas gingivalis is a predominant periodontal pathogen, whose fimbriae are considered to be a major virulence factor, especially for bacterial adherence and invasion of host cells. In the present study, we investigated the influence of fimbriae on the interactions between alphavbeta3- and alpha5beta1-integrins and their ligand extracellular ...
Ichiro Nakagawa +2 more
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Porphyromonas gingivalis is a predominant periodontal pathogen, whose fimbriae are considered to be a major virulence factor, especially for bacterial adherence and invasion of host cells. In the present study, we investigated the influence of fimbriae on the interactions between alphavbeta3- and alpha5beta1-integrins and their ligand extracellular ...
Ichiro Nakagawa +2 more
exaly +3 more sources
"Protein Engineering, Design and Selection", 1989
The pattern of sequence variation between Bacteroides nodosus fimbrial subunits of different serotypes suggests a degree of flexibility, which might be exploited for protein engineering approaches for the expression of other peptides. We have tested this using the well-characterized peptide epitope from VP1 of foot-and-mouth disease virus (FMDV ...
Jennings, P. A. +3 more
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The pattern of sequence variation between Bacteroides nodosus fimbrial subunits of different serotypes suggests a degree of flexibility, which might be exploited for protein engineering approaches for the expression of other peptides. We have tested this using the well-characterized peptide epitope from VP1 of foot-and-mouth disease virus (FMDV ...
Jennings, P. A. +3 more
openaire +4 more sources
Secretion of type-1-fimbriae binding proteins from human neutrophil granulocytes
Inflammation, 1996Granule matrix proteins secreted from human neutrophils after ionomycin stimulation were separated by SDS-PAGE, blotted onto a polyvinylidene diflouride (PVDF) membrane and overlaid with the mannose-binding lectin concanavalin A (Con A) or Escherichia coli bacteria exposing type-I-fimbriae.
A, Karlsson, C, Dahlgren
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Microbial Pathogenesis, 1997
Fimbrial-associated protein, an attachment factor of Actinobacillus actinomycetemcomitans, was genetically analysed by cloning. The plasmid obtained was found to harbor a 1.7kb fragment which contained a 228bp open reading frame encoding 76 amino acids (7.970kDa).
K, Ishihara +4 more
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Fimbrial-associated protein, an attachment factor of Actinobacillus actinomycetemcomitans, was genetically analysed by cloning. The plasmid obtained was found to harbor a 1.7kb fragment which contained a 228bp open reading frame encoding 76 amino acids (7.970kDa).
K, Ishihara +4 more
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Immunoprotective efficacy of 3 Klebsiella pneumoniae type I fimbriae proteins in a murine model
Veterinary MicrobiologyKlebsiella pneumoniae is a primary cause of clinical mastitis in dairy cows, with prevention being crucial, as treatments often fail due to antimicrobial resistance. Recent studies identified type I fimbrial antigens of K. pneumoniae as promising vaccine candidates, but there are limited research data.
John Kastelic
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Developmental and Comparative Immunology, 2004
Liposome-associated fimbriae antigens (SEF14 and SEF21) were prepared for intraocular immunization to seek protective efficacy for intestinal infection with Salmonella enterica serovar Enteritidis. Chickens were immunized intraocularly with the antigens at 8 and 10 weeks of age.
Shinobu Watarai, Tadashi Iwasaki
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Liposome-associated fimbriae antigens (SEF14 and SEF21) were prepared for intraocular immunization to seek protective efficacy for intestinal infection with Salmonella enterica serovar Enteritidis. Chickens were immunized intraocularly with the antigens at 8 and 10 weeks of age.
Shinobu Watarai, Tadashi Iwasaki
exaly +3 more sources