Bordetella pertussis fimbriae are effective carrier proteins in Neisseria meningitidis serogroup C conjugate vaccines. [PDF]
FEMS Immunology and Medical Microbiology, 2001 Serogroup C meningococcal conjugate vaccines generally use diphtheria or tetanus toxoids as the protein carriers. The use of alternative carrier proteins may allow multivalent conjugate vaccines to be formulated into a single injection and circumvent potential problems of immune suppression in primed individuals.
K. Reddin +6 more
semanticscholar +4 more sources
Lrp acts as both a positive and negative regulator for type 1 fimbriae production in Salmonella enterica serovar Typhimurium. [PDF]
PLoS ONE, 2011 Leucine-responsive regulatory protein (Lrp) is known to be an indirect activator of type 1 fimbriae synthesis in Salmonella enterica serovar Typhimurium via direct regulation of FimZ, a direct positive regulator for type 1 fimbriae production.
Chang-Ho Baek +3 more
doaj +1 more source
The role of bacterial secretion systems in the virulence of Gram-negative airway pathogens associated with cystic fibrosis [PDF]
, 2016 Cystic fibrosis (CF) is the most common lethal inherited disorder in Caucasians. It is caused by mutation of the CF transmembrane conductance regulator (CFTR) gene.
Depluverez, Sofie +2 more
core +2 more sources
Protein translation and cell death: the role of rare tRNAs in biofilm formation and in activating dormant phage killer genes. [PDF]
PLoS ONE, 2008 We discovered previously that the small Escherichia coli proteins Hha (hemolysin expression modulating protein) and the adjacent, poorly-characterized YbaJ are important for biofilm formation; however, their roles have been nebulous.
Rodolfo García-Contreras +3 more
doaj +1 more source
Frontiers in Microbiology, 2023 Uropathogenic Escherichia coli (UPEC) is a major causative agent of urinary tract infections. The bacteria internalize into the uroepithelial cells, where aggregate and form microcolonies.
Hidetada Hirakawa +10 more
doaj +1 more source
Everything You Always Wanted to Know About Salmonella Type 1 Fimbriae, but Were Afraid to Ask
Frontiers in Microbiology, 2019 Initial attachment to host intestinal mucosa after oral infection is one of the most important stages during bacterial pathogenesis. Adhesive structures, widely present on the bacterial surface, are mainly responsible for the first contact with host ...
Rafał Kolenda +2 more
semanticscholar +1 more source
Electron Transport Chain Is Biochemically Linked to Pilus Assembly Required for Polymicrobial Interactions and Biofilm Formation in the Gram-Positive Actinobacterium Actinomyces oris. [PDF]
, 2017 The Gram-positive actinobacteria Actinomyces spp. are key colonizers in the development of oral biofilms due to the inherent ability of Actinomyces to adhere to receptor polysaccharides on the surface of oral streptococci and host cells.
Belkys C. Sanchez +5 more
core +2 more sources
Leucine-Responsive Regulatory Protein Lrp and PapI Homologues Influence Phase Variation of CS31A Fimbriae [PDF]
Journal of Bacteriology, 2014 ABSTRACTCS31A, a K88-related surface antigen specified by theclpoperon, is a member of the type P family of adhesive factors and plays a key role in the establishment of disease caused by septicemic and enterotoxigenicEscherichia colistrains. Its expression is under the control of methylation-dependent transcriptional regulation, for which the leucine ...
Graveline, Richard +6 more
openaire +4 more sources
IscR Regulation of Type 3 Fimbriae Expression in Klebsiella pneumoniae CG43
Frontiers in Microbiology, 2017 In Klebsiella pneumoniae, we have previously shown that IscR, an Fe–S cluster-containing transcriptional factor, plays a dual role in controlling capsular polysaccharide biosynthesis and iron-acquisition systems by switching between its holo and apo ...
Tien-Huang Lin +9 more
doaj +1 more source
Std fimbriae-fucose interaction increases Salmonella-induced intestinal inflammation and prolongs colonization [PDF]
, 2019 Author summary The intestinal epithelium is a crucial biological interface, interacting with both commensal and pathogenic microorganisms. It’s lined with heavily glycosylated proteins and glycolipids which can act as both attachment sites and energy ...
Baines, J. +12 more
core +1 more source