Characterization of structural and immunological properties of a fusion protein between flagellin from Salmonella and lumazine synthase from Brucella [PDF]
, 2017 Aiming to combine the flexibility of Brucella lumazine synthase (BLS) to adapt different protein domains in a decameric structure and the capacity of BLS and flagellin to enhance the immunogenicity of peptides that are linked to their structure, we ...
Berguer, Paula Mercedes +11 more
core +3 more sources
Frontiers in Microbiology, 2018 Bacterial host tropism is a primary determinant of the range of host organisms they can infect. Salmonella serotypes are differentiated into host-restricted and host-adapted specialists, and host-unrestricted generalists.
Rafał Kolenda +14 more
doaj +1 more source
Large-scale Quality Control of Cardiac Imaging in Population Studies: Application to UK Biobank [PDF]
, 2019 In large population studies such as the UK Biobank (UKBB), quality control of the acquired images by visual assessment is unfeasible. In this paper, we apply a recently developed fully-automated quality control pipeline for cardiac MR (CMR) images to the
Bai, W. +7 more
core +1 more source
Immunoglobulin domains in Escherichia coli and other enterobacteria: from pathogenesis to applications in antibody technologies [PDF]
, 2012 The immunoglobulin (Ig) protein domain is widespread in nature having a well-recognized role in proteins of the immune system. In this review, we describe the proteins containing Ig-like domains in Escherichia coli and entero-bacteria, reporting their ...
Bluhm, Hendrik +3 more
core +2 more sources
Assessing the diversity of the virulence potential of Escherichia coli isolated from bacteremia in São Paulo, Brazil [PDF]
, 2013 Most of the knowledge of the virulence determinants of extraintestinal pathogenic Escherichia coli (ExPEC) comes from studies with human strains causing urinary tract infections and neonatal meningitis and animal strains causing avian colibacillosis.
Pignatari, Antonio Carlos Campos +3 more
core +1 more source
Bacteria-induced uroplakin signaling mediates bladder response to infection.
PLoS Pathogens, 2009 Urinary tract infections are the second most common infectious disease in humans and are predominantly caused by uropathogenic E. coli (UPEC). A majority of UPEC isolates express the type 1 pilus adhesin, FimH, and cell culture and murine studies ...
Praveen Thumbikat +8 more
doaj +1 more source
Binding site plasticity regulation of the FimH catch-bond mechanism: Molecular Dynamics dataset
, 2023 Olivier Languin–Cattoën +2 more
openalex +1 more source
Survival of FimH-expressing enterobacteria in macrophages relies on glycolipid traffic
Nature, 1997 Strains of Escherichia coli persist within the human gut as normal commensals, but are frequent pathogens and can cause recurrent infection. Here we show that, in contrast to E. coli subjected to opsonic interactions stimulated by the host's immune response, E.
Baorto, D +6 more
openaire +2 more sources
Research in Molecular Medicine, 2016 Background: Urinary tract infections are one of the most frequent health problems and Uropathogenic Escherichia coli is the major pathogen resulting UTIs.
Razieh Molaie +3 more
doaj
Pathogens, 2016 Studies of Uropathogenic Escherichia coli (UPEC) pathogenesis have relied heavily on genetic manipulation to understand virulence factors. We applied a recently reported positive-negative selection system to create a series of unmarked, scarless FimH ...
Varnica Khetrapal +3 more
doaj +1 more source