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Different effects of plasmids harboring <i>bla</i><sub>OXA-232</sub> between major and minor clones in <i>Klebsiella pneumoniae</i>. [PDF]
Cho YY, Kim HW, Kim SH, Wi YM, Ko KS.
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First molecular detection of porcine rotavirus B (RVB) in Poland - case study and genome analysis. [PDF]
Cybulski P +4 more
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Sinteza alfa-D-manoliziranih glikokonjugatov kot antagonistov receptorja FimH
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Sinteza C-manozidov kot potencialnih antagonistov lektinskega receptorja FimH
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Target Selectivity of FimH Antagonists
Journal of Medicinal Chemistry, 2012Mannose-based FimH antagonists are considered new therapeutics for the treatment of urinary tract infections (UTIs). They prevent the adhesion of uropathogenic Escherichia coli (UPEC) to urothelial cell surfaces triggered by the lectin FimH, which is located at the tip of bacterial type 1 pili.
Meike, Scharenberg +3 more
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Nanoscale, 2023
Glycoclusters have been extensively investigated for their inhibition of multivalent carbohydrate-protein interactions, which is often the first step for bacterial and viral pathogens to selectively bind their host cells.
Tao Wang +4 more
semanticscholar +1 more source
Glycoclusters have been extensively investigated for their inhibition of multivalent carbohydrate-protein interactions, which is often the first step for bacterial and viral pathogens to selectively bind their host cells.
Tao Wang +4 more
semanticscholar +1 more source
Future Microbiology, 2023
Background: In this study, uropathogenic Escherichia coli (UPEC) from pregnant and nonpregnant patients were characterized with respect to antimicrobial resistance (AMR) and expression of their virulence factors and cytokines elicited upon infection in ...
Snehashis Koley, M. Mukherjee
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Background: In this study, uropathogenic Escherichia coli (UPEC) from pregnant and nonpregnant patients were characterized with respect to antimicrobial resistance (AMR) and expression of their virulence factors and cytokines elicited upon infection in ...
Snehashis Koley, M. Mukherjee
semanticscholar +1 more source
FimH Antagonists: Phosphate Prodrugs Improve Oral Bioavailability
Journal of Medicinal Chemistry, 2016The widespread occurrence of urinary tract infections has resulted in frequent antibiotic treatment, contributing to the emergence of antimicrobial resistance. Alternative approaches are therefore required. In the initial step of colonization, FimH, a lectin located at the tip of bacterial type 1 pili, interacts with mannosylated glycoproteins on the ...
Kleeb, Simon +7 more
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