Results 251 to 260 of about 13,264 (267)

FimH antagonists – solubility vs. permeability

2016
Urinary tract infections (UTIs) caused by uropathogenic Escherichia coli (UPEC) are among the most prevalent infections worldwide. Since frequent antibiotic treatment favors the emergence of antibiotic resistance, efficient non-antibiotic strategies are urgently needed.
Pang, Lijuan, Bezençon, Jacqueline, Kleeb, Simon, Rabbani, Said, Sigl, Anja, Smiesko, Martin, Sager, Christoph P., Eris, Deniz, Schwardt, Oliver, Ernst, Beat   +9 more
openaire   +2 more sources

Bifunctional mannoside–glucosinolate glycoconjugates as enzymatically triggered isothiocyanates and FimH ligands

Organic & Biomolecular Chemistry, 2018
The synthesis of glucosinolate–mannoside glycoconjugates combining both the structural features of a myrosinase substrate and a FimH ligand is described.
G. Cutolo, F. Reise, M. Schuler, R. Nehmé, G. Despras, J. Brekalo, P. Morin, P.-Y. Renard, T. K. Lindhorst, A. Tatibouët   +9 more
openaire   +3 more sources

Binary CuO\CoO nanoparticles inhibit biofilm formation and reduce the expression of papC and fimH genes in multidrug-resistant Klebsiella oxytoca

Molecular Biology Reports, 2023
Sarah N. Aziz, Israa M. S. Al-Kadmy, A. Rheima, Karrar Jasim Al-sallami, Noura H. Abd Ellah, Gaber El-Saber Batiha, M. El-Bouseary, A. Algammal, H. Hetta   +8 more
semanticscholar   +1 more source

Investigation of the biofilm formation in extra-intestinal pathogenic Escherichia coli ST131 strains and its correlation with the presence of fimH, afa, and kpsMSTII genes

Journal of Applied Genetics, 2023
Marzieh Ebrahimi, Manouchehr Ahmadi Hedayati, Rima Fanaei Pirlar, Newsha Mortazavi, M. Nazari, Amjad Ahmadi, Jaber Hemmati, Y. Erfani   +7 more
semanticscholar   +1 more source

Multivalent calix[4]arene-based mannosylated dendrons as new FimH ligands and inhibitors.

Bioorganic chemistry (Print), 2023
A. Palmioli, L. Moretti, Carlo Alberto Vezzoni, L. Legnani, P. Sperandeo, L. Baldini, F. Sansone, C. Airoldi, A. Casnati   +8 more
semanticscholar   +1 more source

Ultra-slow conformational dynamics and catch bond formation of a Bacterial Adhesin revealed by a single-domain variant of FimH

bioRxiv
Pearl Magala, Lisa M Tuttle, G. Interlandi, Laura A. Carlucci, Molly Y. Mollica, Maria K. Janowska, W. Thomas, E. Sokurenko, Rachel E. Klevit   +8 more
semanticscholar   +1 more source

Charakterisierung der Zellbindungs- und Internalisierungseigenschaften eines FimH Teilpeptids

Bestimmte pathogene E. coli Spezies verfügen über das Adhäsin FimH, mit dem sie sich sowohl in der Blase als auch im Darm anheften. Im Zuge dessen können sie internalisiert werden und Infektionen wie Harnwegsinfektionen und Colitis auslösen. FimH als Targeter zu nutzen, um Arzneistoffe an die Glykokalyx des Urothels oder der Mukosa des Darms zu binden,
openaire   +1 more source

The artificial neural network selects saccharides from natural sources a promise for potential FimH inhibitor to prevent UTI infections

In Silico Pharmacology
M. Dhanalakshmi, Medha Pandya, D. Sruthi, K. R. Jinuraj, Kajari Das, Ayushman Gadnayak, Sushma Dave, N. Andal   +7 more
semanticscholar   +1 more source

Detection of fimH, kpsMTII, hlyA, and traT genes in Escherichia coli isolated from Iraqi patients with cystitis

Gene Reports, 2022
Raad N. Hasan, S. A. Jasim, Y. Ali
semanticscholar   +1 more source

Involvement of adhesins (EcpD, FdeC, FimH) expressed in mammary pathogenic Escherichia coli on adhesion to bovine mammary epithelial cells

Antonie van Leeuwenhoek
Yusaku Tsugami, Taketoshi Iwata, Aoi Sugiyama, Megumi Onishi, Kei-ichi Nakajima, Makoto Osaki, Y. Nagasawa   +6 more
semanticscholar   +1 more source