Results 61 to 70 of about 4,839,506 (299)

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source

Convolutions with probability densities and applications to PDEs

Electronic Journal of Differential Equations, 2017
In this article we introduce several new convolution operators, generated by some known probability densities. By using the inverse Fourier transform and taking inverse steps (in the analogues of the classical procedures used for example in the heat ...
Sorin G. Gal
doaj  

Cognitive Functioning in Vorinostat‐Treated Pediatric and Young Adult Patients Over the First 180 Days After Hematopoietic Stem Cell Transplant

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba, Michelle Rozwadowski, Thomas Braun, April Rahrig, Edward Peres, Kirsten M. Williams, Vanessa Fabrizio, Julie‐An Talano, Carrie L. Kitko, Nicolas Parnell, Pavan Reddy, Sung Won Choi   +11 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

A modified Tikhonov regularization method for a class of inverse parabolic problems

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2020
This paper deals with the problem of determining an unknown source and an unknown initial condition in a abstract final value parabolic problem. This problem is ill-posed in the sense that the solutions do not depend continuously on the data.
Saouli Nabil, Zouyed Fairouz
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Dynamics with Infinitely Many Derivatives: The Initial Value Problem

, 2008
Differential equations of infinite order are an increasingly important class of equations in theoretical physics. Such equations are ubiquitous in string field theory and have recently attracted considerable interest also from cosmologists.
A. Kilbas, A. Ludu, A.A. Gerasimov, A.D. Polyanin, A.S. Koshelev, B. Dragovich, D.V. Prokhorenko, E. Coletti, G. Calcagni, G. Calcagni, H.T. Davis, H.T. Davis, I. Ellwood, I.Y. Aref'eva, I.Y. Aref'eva, I.Y. Aref'eva, I.Y. Aref'eva, I.Y. Aref'eva, J.A. Minahan, L. Carleson, M. Kiermaier, M. Ostrogradski, M. Schnabl, M. Taylor, M.E. Soussa, N. Barnaby, N. Barnaby, N. Barnaby, N. Barnaby, N. Hayashi, N. Jokela, N. Moeller, N. Moeller, Neil Barnaby, Niky Kamran, R. Bryant, R.D. Carmichael, R.L.P.G. do Amaral, R.P. Woodard, S. Coleman, T. Biswas, T. Biswas, T. Erler, T. Lalesco, V.S. Vladimirov, W. Siegel, W. Taylor, W.T. Thomson, Y. Okawa, Y. Volovich, Y. Volovich   +50 more
core   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Precise geoid computation using Stokes-Helmert's scheme and strict integrals of topographic effects

Geodesy and Geodynamics, 2019
The high-precision local geoid model was computed based on the improved Stokes-Helmert′s boundary value problem and strict integrals of topographic effects. This proposed method involves three steps.
Dongmei Guo, Huiyou He, Peng Sang
doaj   +1 more source

A final value problem with a non-local and a source term: regularization by truncation [PDF]

, 2023
Subhankar Mondal
openalex   +1 more source