Results 71 to 80 of about 4,839,506 (299)
A convergent string method: Existence and approximation for the Hamiltonian boundary-value problem [PDF]
, 2015 This article studies the existence of long-time solutions to the Hamiltonian boundary value problem, and their consistent numerical approximation. Such a boundary value problem is, for example, common in Molecular Dynamics, where one aims at finding a ...
Schwetlick, Hartmut, Zimmer, Johannes
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Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Operational WKB solution to the initial/final-value problem for Beechem-Haas equations
Electronic Journal of Differential Equations, 2000 Operational and Wantzel-Kramers-Brillouin (WKB) methods are utilized to obtain an analytical approximate solution of the Beechem-Haas equation for the initial/final-value problem with system parameters of radial profile.
Valentino Anthony Simpao
doaj
Optimization of the Forcing Term for the Solution of Two-Point Boundary Value Problems
Journal of Mathematics, 2013 We present a new numerical method for the computation of the forcing term of minimal norm such that a two-point boundary value problem admits a solution. The method relies on the following steps.
Gianni Arioli
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Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
An Impact of Improvement-Exchange Heuristics to Quality of Probabilistic TSP Solution
Communications, 2003 This paper deals with a probabilistic travelling salesman problem (PTSP), which differs from a travelling salesman problem (TSP) [6] in the demand for a customer visit. In PTSP is each customer visited with a given probability only. An objective function
Jaroslav Janacek, Juraj Hurtik
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Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Selecciones Matemáticas, 2020 In this article, we first prove that the initial value problem associated to the homogeneous wave equation in periodic Sobolev spaces has a global solution and the solution has continuous dependence with respect to the initial data, in [0; T], T > 0.
Yolanda Santiago Ayala +1 more
doaj +1 more source
Understanding the Backlog Problems Associated with Requests for Continued Examination Practice [PDF]
, 2015 One of the greatest problems facing the current patent administration is a long patent pendency period. This study focuses on Request for Continued Examination (RCE) practice, and its effects on the current patent application backlog problem.
Tu, Sean
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A Real-Time Solver For Time-Optimal Control Of Omnidirectional Robots with Bounded Acceleration
, 2018 We are interested in the problem of time-optimal control of omnidirectional robots with bounded acceleration (TOC-ORBA). While there exist approximate solutions for such robots, and exact solutions with unbounded acceleration, exact solvers to the TOC ...
Balaban, David +2 more
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