Results 71 to 80 of about 793,305 (259)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

The impact of ISO 14001 standards and non-financial reporting on companies' financial performance [PDF]

Anali Ekonomskog fakulteta u Subotici
In today's dynamic business environment, companies increasingly understand how important care for the environment is for the success of their operations. There is an increasing number of companies that implement the ISO 14001 standard in their operations.
Jovanović Dejan, Vuković Ivana, Todorović Mirjana   +2 more
doaj   +1 more source

System of Non-Financial Performance Indicators in the Manufacturing Sector

Administrative Sciences
The growing demand for transparency in sustainability reporting has compelled enterprises to look far beyond the boundaries of classical financial ratios when assessing their own performance. Environmental, social, and governance (ESG) indicators have dominated recent academic debate—primarily because of mounting regulatory and societal pressure.
Rasa Subačienė, Iluta Arbidane, Iveta Mietule, Inta Kotane, Astra Auzina-Emsina, Natalja Lace   +5 more
openaire   +2 more sources

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

AKUNTABILITAS DAN PENGUKURAN KINERJA PEMERINTAHAN

Jurnal Akuntansi dan Keuangan, 2000
Accountability is one of the main focuses in achieving the good governance in Indonesia recently. The government will be asked to submit the report about the results of many programs which have already been undertaken.
Arja Sadjiarto
doaj  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Determinants of Financial Performance Using Islamic Social Responsibility as an Intervening Variable in Sharia Commercial Banks in Indonesia

Indonesian Interdisciplinary Journal of Sharia Economics
Financial performance describes the company's financial condition in a certain period, both regarding raising funds and distributing funds, which is usually measured by capital adequacy, liquidity, and profitability indicators.
Gustin Tamara Simanungkalit, Nurlaila Nurlaila, Nur Ahmadi Bi Rahmani   +2 more
doaj   +1 more source

Zkoumání dopadu podnikoých charakteristik na výkonnost podniku [PDF]

Trendy v podnikání, 2016
This article point out on importance of non-financial aspect of business performance. Research confirms that non-financial performance determinants either directly or as an intermediary mechanisms affect financial performance, however it is also ...
Petra Štamfestová
doaj