Results 61 to 70 of about 3,445,117 (299)

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas   +3 more
wiley   +1 more source

Property rights in financial transactions [PDF]

open access: yesAmicus Curiae, 2012
Alastair Hudson analyses House of Lords’ decisions in interest rate swaps cases and suggests new ways in which the principles of equity might be applied to solve the problems which arise. Article by Alastair Hudson (Queen Mary, University of London) published in Amicus Curiae - Journal of the Institute of Advanced Legal Studies and its Society for ...
openaire   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

The Effect of Common Law (‘urf) in Spouses’ Rights [PDF]

open access: yesفقه و حقوق خانواده, 2010
In the definition of spouses’ rights, common law is considered as an effective factor. Clarification of such rights may help the strengthening of family foundations, while the lack of clarification may be an adverse factor in the establishment of family ...
Maryam Ibn-Torab
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Financial Deepening, Property Rights, and Poverty: Evidence from Sub-Saharan Africa

open access: yes, 2015
The recent financial crisis has brought to the forefront renewed concerns about the merit of financial development, especially for the most vulnerable segments of our population.
R. Singh, Yifei Huang
semanticscholar   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Digital technologies in investment activities

open access: yesE-Management
The issues of development of digital financial technologies in the Russian Federation (hereinafter referred to as RF, Russia) are investigated. The article considers foreign and domestic experience of using digital technologies in financial and ...
V. V. Prokhorov, I. P. Rozhnov
doaj   +1 more source

Corporate Voluntary Disclosure and Separation of Cash Flow Rights From Control Rights [PDF]

open access: yesمجله دانش حسابداری, 2016
This study examines special aspect of interest conflict in the relationship between shareholders and voluntary disclosure in financial reporting.
MohamadAli Aghaei   +2 more
doaj   +1 more source

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