Results 71 to 80 of about 2,993,511 (277)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
The Effect of Common Law (‘urf) in Spouses’ Rights [PDF]
فقه و حقوق خانواده, 2010 In the definition of spouses’ rights, common law is considered as an effective factor. Clarification of such rights may help the strengthening of family foundations, while the lack of clarification may be an adverse factor in the establishment of family ...
Maryam Ibn-Torab
doaj +1 more source
Re-Imagining the Workplace as a Hub for Financial Wellness [PDF]
, 2018 Financial concerns are Americans' number one source of stress. For employees, financial worries affect their focus and productivity on the job, leading to profitability losses for companies.
Neighborhood Trust Financial Partners
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Investorsâ Rights Protection on a Global Financial Market [PDF]
International Journal of Academic Research in Business and Social Sciences, 2014 In the last decades, we have been faced with a rapid development and sophistication of the investing methods that investors have at their disposal. The emergence of new micro and macroeconomic risks that have affected the markets stability, impose the re-analyzing of the prudential regulations in the field of investors’ rights protection.
Flavia-Mirela Barna +1 more
openaire +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Property rights in financial transactions [PDF]
Amicus Curiae, 2012 Alastair Hudson analyses House of Lords’ decisions in interest rate swaps cases and suggests new ways in which the principles of equity might be applied to solve the problems which arise. Article by Alastair Hudson (Queen Mary, University of London) published in Amicus Curiae - Journal of the Institute of Advanced Legal Studies and its Society for ...
openaire +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Corporate Voluntary Disclosure and Separation of Cash Flow Rights From Control Rights [PDF]
مجله دانش حسابداری, 2016 This study examines special aspect of interest conflict in the relationship between shareholders and voluntary disclosure in financial reporting.
MohamadAli Aghaei +2 more
doaj +1 more source