Results 41 to 50 of about 793,023 (271)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Aspects Regarding Policy and the Financing Mechanism of the Consolidated General Deficitary Budget [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2016
The purpose of the paper is the quantification and identification of the mechanism of financing the general government deficit. The theme of this paper is topical because the issue of the budget deficit is a topical issue both within the scientific ...
Maria Felicia Chirculescu
doaj  

Analysis of Internal and External Funding Mechanisms Considering Green Consumer Loyalty: A Game-Theoretic Approach

open access: yesIEEE Access, 2020
Since financing issues of research and development (R&D) directly determine the success of green supply chain initiatives, the choice of funding mechanisms becomes key for green supply chain participants.
Weimin Ma, Ranran Zhang, Zhengrong Cheng
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Review of Multi-Agent Game in Intellectual Property Pledge Financing

open access: yesJournal of Risk Analysis and Crisis Response (JRACR)
To promote the theoretical research and business development of intellectual property pledge financing, this paper summarizes the research status of multi-agent game in intellectual property pledge financing. At present, scholars’ research on multi-agent
Chang Guo
doaj   +1 more source

Peran Instrumen Keuangan Negara Cash Waqf Linked Sukuk Dalam Meningkatkan Pembiayaan Ekspor UMKM Indonesia

open access: yesEl-Jizya: Jurnal Ekonomi Islam
The aim of this research is to examine the role of the Cash Waqf Linked Sukuk instrument in increasing export financing for Indonesian MSMEs. This research employs a descriptive qualitative approach using secondary data obtained from literature studies.
Annisa Rahma Febriyanti   +1 more
doaj   +1 more source

Size and soft budget constraints [PDF]

open access: yes, 2006
There is much evidence against the so-called "too big to fail" hypothesis in the case of bailouts to sub-national governments. We look at a model where districts of different size provide local public goods with positive spillovers.
Crivelli, Ernesto, Staal, Klaas
core   +5 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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