Results 91 to 100 of about 16,896 (199)

The Role of Reactive Oxygen Species, Inflammation, and Endoplasmic Reticulum Stress Response in the Finasteride Protective Effect against Benign Prostate Hyperplasia

The World Journal of Men's Health
Purpose: Benign prostate hyperplasia (BPH) is a common age-related chronic condition. Its pathogenesis involves androgen imbalance, inflammation, oxidative stress, and endoplasmic reticulum (ER) stress.
Geum-Hwa Lee, Hwa-Young Lee, Luo Zhao, Mohammad Mamun Ur Rashid, Myung Ki Kim, Young Beom Jeong, Han-Jung Chae, Yu Seob Shin   +7 more
doaj   +1 more source

Effetivity assesssment of masculine androgenetic alopecia treatment with finasteride, topic minoxidil and finasteride and minoxidil association

, 2002
Fundamentos: A alopecia androgenetica consiste na perda de cabelos induzida por androgenos em individuos geneticamente suscetiveis. Ocorre uma progressiva miniaturizacao dos foliculos, estando implicada em sua patogenese uma heranca de padrao poligenico ...
Padilha, Maria Helena Valle de Queiroz [UNIFESP]
core  

Safety, tolerability, and pharmacokinetics of CG2001 in Chinese adult male subjects with androgenetic alopecia: a randomized, double-blind, placebo-controlled, single- and multi-doses, phase 1 clinical study

Journal of Dermatological Treatment
Objectives Compared with placebo, this phase I study evaluated the safety, tolerability, and pharmacokinetics of CG2001, a novel isopropyl alcohol-free minoxidil-finasteride combination topical foam, in Chinese males with androgenetic alopecia (AGA ...
Yanting Li, Baohui Yu, Suping Niu, Ziyan Ding, Qun Gu, Hui Zhang, Rui Ding, Cheng Zhou, Fang Men, Yian Liu, Wenyan Zhao, Liming Chen, Shuang Li, Qian Wang, Meng Xiao, Fan Huang, Binyi Hu, Jiaojiao Zhang, Jianzhong Zhang, Yi Fang   +19 more
doaj   +1 more source

Impact of finasteride on modulating the risk and clinical outcomes of bladder cancer: insights from a comprehensive meta-analysis

Frontiers in Pharmacology
PurposeNumerous prior analyses have highlighted a potential link between androgen suppression therapy (AST) and bladder cancer (BCa). However, there is a notable gap in research specifically examining the influence of finasteride on BCa risk and clinical
Ailing Yu, Ailing Yu, Ailing Yu, Ailing Yu, Ailing Yu, Zian Bai, Zian Bai, Zian Bai, Zian Bai, Yijie Wang, Yijie Wang, Yijie Wang, Yijie Wang, Zhen Luo, Zhen Luo, Zhen Luo, Zhen Luo, Xiaochen Du, Mengxin Chen, Shuang Wen, Honglong Wang, Xiaoying Yuan, Chunyu Yang, Shanshan Bai, Bo Fan, Bo Fan, Bo Fan, Bo Fan   +27 more
doaj   +1 more source

Finasteride and Fertility: Case Report and Review of the Literature

, 2012
Although millions of men have taken or are taking finasteride, there are no documented cases of successful pregnancy in the literature after discontinuation of the drug. Early studies did not show significant influence of finasteride on semen parameters,
M. De Santis, RICCI, GIUSEPPE, S. Luppi, LO BELLO, LEILA, K. Skerk, M. Martinelli, ZITO, GABRIELLA   +6 more
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Finasteride and Bladder Cancer

, 2016
this di bladder cancer are intriguing. This is of specific interest, higher than in women [12]. Part of the difference may be EU RO P E AN URO LOGY 6 9 ( 2 0 1 6) 4 1 1 – 4 1 2 ava i lable at www.sciencedirect.com journal homepage: www.europeanurology ...
Carlo La Vecchia, C. La Vecchia
core   +1 more source

Identification and validation of synergistic drug strategies targeting macrophage polarization in triple-negative breast cancer via single-cell transcriptomics and deep learning

Translational Oncology
Triple-negative breast cancer (TNBC) presents therapeutic challenges due to its immunosuppressive tumor microenvironment (TME) and limited targeted options. Analyzing scRNA-seq data from 24 TNBC patients using integrated transcriptomics, machine-learning,
Qi Qi, Wenhao Yang, Liang Li, Yuheng Tang, Yongzhi Chen, Hui Wang, Sun Yingjie, Jialin Shi, Samina Gul, Wenru Tang, Jianyu Pang, Xiaoli Xie   +11 more
doaj   +1 more source

Mean finasteride levels (ng/mL) stratified by categories of demographic measures among treatment-compliant men in the Prostate Cancer Prevention Trial finasteride arm.

, 2016
Mean finasteride levels (ng/mL) stratified by categories of demographic measures among treatment-compliant men in the Prostate Cancer Prevention Trial finasteride arm.
Cindy H. Chau (2211118), Juergen K. V. Reichardt (233804), Catherine M. Tangen (2211112), Cathee Till (2211115), Teresa L. Johnson-Pais (2211121), Howard L. Parnes (2211130), Xiaohong Chen (220164), Ian M. Thompson (307836), Robin J. Leach (2211127), Ann W. Hsing (219496), Ashraful Hoque (2211109), Jeannette M. Schenk (2211124), Phyllis J. Goodman (709482), Douglas K. Price (220746), Lisa Chu (763073), William D. Figg (220748)   +15 more
core   +1 more source

[New prospective therapy for benign prostatic hyperplasia with finasteride]. FT Nuove prospettive terapeutiche nella iperplasia prostatica benigna con la Finasteride.

, 1993
A randomized, double blind, placebo-controlled study (placebo and Finasteride 1 or 5 mg/die) was carried out in 34 patients with benign prostatic hyperplasia (BPH). After 12 months of treatment all patients received Finasteride 5 mg/die. Follow-up ranges
Miano L, Manieri C, PARADISO GALATIOTO, Giuseppe, VICENTINI, Carlo   +3 more
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The effects of Finasteride on parity in female drosophila melanogaster [PDF]

Finasteride has been used to treat male pattern baldness and benign prostate hyperplasia, and could potentially treat female pattern baldness and polycystic ovary syndrome.
Young, Zachary, Mitchell, Carol, Horspool, William, Bastos, Miguel, Fleming, Alesha, Sandell, Dominic   +5 more
core   +1 more source