Results 71 to 80 of about 24,950 (282)
5-alpha-reductase is involved as a rate-imitating enzyme in the metabolism of steroids. Several 5-alpha-reduced steroids such as dihydrotestosterone, allopregnanolone or tetrahydrocorticosterone have neurotrophic, neuroprotective, and anxiolytic ...
Römer, Benedikt, Gass, Peter
core +1 more source
Systemic Absorption and Pharmacokinetics of Five Novel Topical Dermatologic Agents: A Review
ABSTRACT In recent years, innovative topical medications with novel mechanisms of action have emerged to treat common dermatologic conditions such as acne, atopic dermatitis, vitiligo, and actinic keratoses. These molecularly targeted therapies offer improved safety and tolerability compared to traditional options like corticosteroids.
Mary Dyson +4 more
wiley +1 more source
The postfinasteride syndrome; an overview
As a 5-α reductase inhibitor, Finasteride has proven effective in ameliorating two conditions documented to be androgen dependent, namely male androgenic alopecia and benign prostatic hyperplasia. Therapeutic results are maintained as long as the drug is
David L. Rowland +9 more
doaj
Metabolism of anabolic androgenic steroids is important for its physiological effects. The aim was to investigate the effects of finasteride (a 5α-reductase inhibitor - 5αR) on cardiac and mutagenic effects promoted by ND. Male Wistar rats were separated
Elizângela Faustino Da Mata +8 more
doaj +1 more source
A modified coaxial electrospinning was conducted to prepare core–sheath nanofibers. They have transdermal enhancer sodium dodecyl sulfate (SDS) and soluble polyvinylpyrrolidone in their sheaths, and finasteride and insoluble ethylcellulose in the cores.
Liang Sun +4 more
wiley +1 more source
To investigate the clinical efficacy and safety of the finasteride (5 mg/day) plus flutamide (125 mg/day) combination therapy in unselected women with hirsutism, 44 women were involved in the study. The effects of such combination treatment have not been
Ozel, D. +4 more
core +1 more source
ABSTRACT Skin boosters are increasingly used to improve dermal quality through injectable and device‐assisted approaches; however, definitions and clinical evidence remain heterogeneous. Aims To provide an updated overview and propose a practical classification of skin boosters, including mechanisms, delivery methods, clinical outcomes, and limitations.
Kyu‐ho Yi +7 more
wiley +1 more source
Post-finasteride syndrome: An emerging clinical problem
The presence of side effects during pharmacological treatment is unfortunately a quite common problem. In this review, we focused our attention on adverse events related to 5 alpha-reductase (5α-R) inhibitors (i.e., finasteride and dutasteride), approved
S. Diviccaro, R. Melcangi, S. Giatti
semanticscholar +1 more source
BackgroundPostmarketing pharmacovigilance data have raised concerns regarding the potential cognitive effects associated with finasteride administration.
Hao Zhang +5 more
doaj +1 more source
The effect of short-term use of finasteride versus cyproterone acetate on perioperative blood loss with monopolar transurethral resection of prostate [PDF]
Shabieb A. Abdelbaki +4 more
openalex +1 more source

