Results 51 to 60 of about 21,530 (198)
Abstract Ageing leads to an increased prevalence of sarcopenia and frailty, characterised by progressive declines in muscle strength, power and function and reduced physical activity. Hot water immersion (HWI) could potentially improve muscle function, but this is yet to be explored in older adults.
Daniel D. Piccolo +12 more
wiley +1 more source
Androgen Receptor (AR) Gene (CAG)n and (GGN)n Length Polymorphisms and Symptoms in Young Males With Long-Lasting Adverse Effects After Finasteride Use Against Androgenic Alopecia [PDF]
INTRODUCTION: Long-term adverse symptoms of men who used oral finasteride against androgenic alopecia have been recently described as post-finasteride syndrome (PFS).
Cauci, Sabina +6 more
core +2 more sources
Bedside risk score for medical therapy failure in small‐volume BPH: Temporal validation
Abstract Purpose Medical therapy is the first‐line treatment for lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH). However, predictors of treatment failure in men with small prostate volume (<30 ml) remain poorly defined.
Numan Alam +8 more
wiley +1 more source
Persistent Sexual, Emotional, and Cognitive Impairment Post-Finasteride
Finasteride is a synthetic 5-α reductase inhibitor, which prevents the conversion of testosterone to dihydrotestosterone and has been used for more than 20 years in the treatment of male pattern hair loss.
Christine Anne Ganzer PhD +2 more
doaj +1 more source
A new pharmacological target for Tourette Syndrome? [PDF]
Tourette Syndrome (TS) is a childhood-onset neurological disorder characterised by multiple motor tics and one or more phonic tics. Number, frequency and tic complexity vary over time.
Frau, Roberto
core +1 more source
Background Benign prostatic hyperplasia affects older men. This systematic review determined efficacy and adverse effects of finasteride. Review methods PubMed, the Cochrane Library, reference lists of reports, and reviews were searched for randomised ...
Moore R Andrew, Edwards Jayne E
doaj +1 more source
The influence of age and the presence of prostate cancer on prostate volume, PSA and PSA density
Objective To assess prostate volume (PV) changes with age in symptomatic and asymptomatic men with and without clinically significant prostate cancer (csPCa). In symptomatic patients, we additionally analysed the effect of age and csPCa on PSA and PSA‐density (PSA‐D) and compared these to current National Institute for Health and Care Excellence (NICE)
Jill Rusbridge +4 more
wiley +1 more source
Flutamide-induced hypospadias in rats: A critical assessment. [PDF]
This paper provides the first detailed description of flutamide-induced hypospadias in the rat based upon wholemount, histologic, three-dimensional reconstruction, scanning electron microscopic, and immunocytochemical analysis.
Baskin, Laurence +4 more
core +2 more sources
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia +6 more
wiley +1 more source
Metabolism of anabolic androgenic steroids is important for its physiological effects. The aim was to investigate the effects of finasteride (a 5α-reductase inhibitor - 5αR) on cardiac and mutagenic effects promoted by ND. Male Wistar rats were separated
Elizângela Faustino Da Mata +8 more
doaj +1 more source

