Results 51 to 60 of about 24,950 (282)

Synthesis and bioactivity of new Finasteride conjugate

, 2011
Finasteride is a synthetic 4-azasteroid compound that acts by inhibiting type II 5 alpha-reductase, the enzyme that converts the androgen testosterone to 5 alpha-dihydrotestosterone.
Li JF, Yu Dahai, Wang ES, Liang Yongtao, Yu Jing, Yu J, Wu JZ, Yang LJ, Li Z, Yu DH, Zhao S, Liang YT, Li Zhuo, Li Jinfeng, Zhao Shuang, Fang Xuexun, Fang XX, Wu Jiazhen, Yang Lijuan, Wang En-si   +19 more
core   +1 more source

Nocturnal awakening secondary to pain in sleep‐related painful erection: A case report and literature review

Sleep Research, EarlyView.
Abstract A 41‐year‐old male patient presented with a 13‐year history of recurrent nocturnal penile pain associated with erections during sleep. Over the course of his illness, the patient attended outpatient clinics on 298 occasions and was hospitalized three times. The primary symptom reported was erectile pain occurring during sleep.
Liping Zhang, Jinxiang Cheng, Jiaxiu He, Rui Guo, Changjun Su, Xianchao Zhao   +5 more
wiley   +1 more source

The ‘Prostate Cancer Screening for People at Genetic Risk of Aggressive Disease’ (PATROL) study

BJU International, EarlyView.
Background Inherited (germline) pathogenic and likely pathogenic variants (gPVs) in key genes associated with increased risk of prostate cancer (PCa) now warrant more attentive PCa screening per National Comprehensive Cancer Network (NCCN) guidelines—e.g., BRCA2, HOXB13, ATM, BRCA1, MSH2, MSH6, CHEK2 and TP53.
Heather H. Cheng, Kara N. Maxwell, Keyan Salari, Matthew R. Cooperberg, Kristin Follmer, Joanne M. Jeter, Grace Jun, Daniel J. Lee, Hiten D. Patel, Edward M. Schaeffer, Alexandra O. Sokolova, Erika M. Wolff, Daniel W. Lin   +12 more
wiley   +1 more source

Treatment Patterns in Pediatric Hidradenitis Suppurativa: Time to Treatment Initiation, Initial Treatment, and Time to Switching

Pediatric Dermatology, EarlyView.
ABSTRACT Background Hidradenitis suppurativa (HS) causes significant morbidity in children. Treatment patterns across sex, race, and ethnicity in pediatric HS have not been thoroughly evaluated. We aim to characterize treatment patterns in pediatric HS, including (1) time to treatment initiation, (2) first prescribed HS treatment, and (3) time to ...
Shaliz Aflatooni, Andrea Ure, Kimberly Smart, Julian A. Cortes, Gabriela Palma, Nicole Johnsen, Yvonne Nong, April W. Armstrong   +7 more
wiley   +1 more source

Comparison between dutasteride and finasteride in hair regrowth and reversal of miniaturization in male and female androgenetic alopecia: a systematic review

Dermatology Reports
Nowadays androgenetic alopecia (AGA) has become a common concern of affected subjects of both sexes. Finasteride is approved by the Food and Drug Administration for the treatment of male AGA.
Almuntaserbellah Almudaimeegh, Hanadi AlMutairi, Fatimah AlTassan, Yomna AlQuraishi, Khalid Nabil Nagshabandi   +4 more
doaj   +1 more source

The effect of 3-month finasteride challenge on biomarkers for predicting cancer outcome on biopsy: Results of a randomized trial.

PLoS ONE, 2018
BackgroundFinasteride, a 5-alpha reductase inhibitor may have effects on biomarkers such as prostate-specific antigen (PSA) that could be leveraged to improve screening.ObjectiveTo determine the predictive characteristics of biomarkers for prostate ...
Javier Hernandez, Jonathan Gelfond, Martin Goros, Michael A Liss, Yuanyuan Liang, Donna Ankerst, Ian M Thompson, Robin J Leach   +7 more
doaj   +1 more source

Efficacy of finasteride for treating patients with androgenetic alopecia who are pileous in other areas: A pilot study in Japan

Indian Journal of Dermatology, 2014
Background: Androgenetic alopecia (AGA) involves androgen-dependent hair loss and finasteride is an established treatment for the disease. However, reports of the influence of finasteride on hair growth in other areas of the body are lacking.
Toru Inadomi
doaj   +1 more source

Effect of repeated hot water immersion on cognitive performance, cerebrovascular function, sleep and biomarkers of neurodegeneration in older adults

Experimental Physiology, EarlyView.
Abstract Ageing is associated with cognitive decline and increased risk of developing neurodegenerative disease. Repeated passive heating, using hot water immersion (HWI), may improve cognitive performance via improved cerebral oxygenation, but this is yet to be examined in older adults.
Daniel D. Piccolo, Jo Corbett, Joseph T. Costello, Thomas B. Williams, Thomas J. James, Janis K. Shute, Mohammad G. A. Alnajjar, Luke C. Hudson, Poppy A. Marsh, Veronika Praskacova, Harry S. Mayes, Michael Tipton, Maria Perissiou, Melitta A. McNarry, Kelly A. Mackintosh, Zoe L. Saynor, Anthony I. Shepherd   +16 more
wiley   +1 more source

Frozen-Thawed Sperm Analysis of Benign Prostatic Hyperplasia Dogs Treated With Finasteride

Frontiers in Veterinary Science, 2022
Benign Prostatic Hyperplasia (BPH) is a pathological condition that directly interferes with the reproductive potential of senile dogs, by leading to prostate enlargement and sperm injury, which in turn may compromise sperm freezeability.
Renato Bueno Flores, Daniel de Souza Ramos Angrimani, Maira Morales Brito, Leticia Lima de Almeida, João Vitor Menezes Lopes, João Diego de Agostini Losano, Camila Infantosi Vannucchi   +6 more
doaj   +1 more source

Effect of repeated hot water immersion on muscle strength, power, function and physical activity in healthy older adults: A randomised crossover trial

Experimental Physiology, EarlyView.
Abstract Ageing leads to an increased prevalence of sarcopenia and frailty, characterised by progressive declines in muscle strength, power and function and reduced physical activity. Hot water immersion (HWI) could potentially improve muscle function, but this is yet to be explored in older adults.
Daniel D. Piccolo, Jo Corbett, Timothy A. Exell, Joseph M. Moore, Amy Wright, Mohammad G. A. Alnajjar, Luke C. Hudson, Poppy A. Marsh, Veronika Praskacova, Melitta A. McNarry, Kelly A. Mackintosh, Zoe L. Saynor, Anthony I. Shepherd   +12 more
wiley   +1 more source