Results 51 to 60 of about 17,467 (192)

The postfinasteride syndrome; an overview

Journal of Mind and Medical Sciences, 2016
As a 5-α reductase inhibitor, Finasteride has proven effective in ameliorating two conditions documented to be androgen dependent, namely male androgenic alopecia and benign prostatic hyperplasia. Therapeutic results are maintained as long as the drug is
David L. Rowland, Ion G. Motofei, Florian Popa, Vlad D. Constantin, Adriana Vasilache, Ioana Paunica, Cristian Bălălău, Georgeta P. Păunică, Petrisor Banu, Stana Păunică   +9 more
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, Volume 20, Issue 11, Page 2647-2655, November 2026.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Finasteride in the treatment of clinical benign prostatic hyperplasia: A systematic review of randomised trials

BMC Urology, 2002
Background Benign prostatic hyperplasia affects older men. This systematic review determined efficacy and adverse effects of finasteride. Review methods PubMed, the Cochrane Library, reference lists of reports, and reviews were searched for randomised ...
Moore R Andrew, Edwards Jayne E
doaj   +1 more source

Finasteride promotes worsening of the cardiac deleterious effects of nandrolone decanoate and protects against genotoxic and cytotoxic damage

Brazilian Journal of Pharmaceutical Sciences, 2020
Metabolism of anabolic androgenic steroids is important for its physiological effects. The aim was to investigate the effects of finasteride (a 5α-reductase inhibitor - 5αR) on cardiac and mutagenic effects promoted by ND. Male Wistar rats were separated
Elizângela Faustino Da Mata, Andrews Marques do Nascimento, Ewelyne Miranda de Lima, Ieda Carneiro Kalil, Denise Coutinho Endringer, Dominik Lenz, Nazaré Souza Bissoli, Girlandia Alexandre Brasil, Tadeu Uggere de Andrade   +8 more
doaj   +1 more source

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

Advanced Science, Volume 13, Issue 61, 3 November 2026.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo, Ke Fang, Changjiang Zhao, Jiachao Xiong, Yuan Zhu, Mingyang Lu, He Yan, Zihan Li, Baojin Wu, Hua Jiang, Yufei Li   +10 more
wiley   +1 more source

Association between finasteride with subjective memory deficits: a study from the NHANES and FAERS databases

Frontiers in Neurology
BackgroundPostmarketing pharmacovigilance data have raised concerns regarding the potential cognitive effects associated with finasteride administration.
Hao Zhang, Hongqi Ou, Panli Zhao, Xi Luo, Ping Zhang, Hua Huang   +5 more
doaj   +1 more source

The impact of 5‐alpha reductase inhibitors on multiparametric MRI diagnostic performance and prostate‐specific antigen density triage: A systematic review

BJUI Compass, Volume 7, Issue 11, November 2026.
Abstract Objectives To evaluate the impact of 5‐alpha reductase inhibitor (5‐ARI) exposure on multiparametric MRI (mpMRI) diagnostic performance for clinically significant prostate cancer (csPCa) and to assess whether standard prostate‐specific antigen density (PSAD)‐gated biopsy thresholds remain safe in this population.
Gregory Harrison, Bogdan Toia, Anju Sahdev, Prabhakar Rajan, Benjamin W. Lamb   +4 more
wiley   +1 more source

A Review on Finasteride: A 5-Alpha Reductase Inhibitors, its Mechanism, Facts and Benefits [PDF]

, 2019
This review gives the information about the Finasteride i.e. 5alpha-reductase inhibitor. Primarily finasteride isused to treat BPH i.e benign prostatic hyperplasia and male androgenetic alopecia.
Karwa, Pawan N., Nemane, Shraddha T., Bhusnure, Omprakash G., Gholve, Sachin B., Mitakari, Pooja R.   +4 more
core   +1 more source

Renin–Angiotensin System Inhibitor Use and Cancer Incidence Among UK Biobank Participants: A Prospective Cohort Study

Cancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Background Renin‐angiotensin system (RAS) inhibitors may influence cancer incidence, but previous findings have been inconsistent. We aimed to evaluate the associations of RAS inhibitor use with overall and site‐specific cancer incidence. Materials and Methods Participants receiving antihypertensive treatment without prior invasive cancer ...
Xuyuan Shi, Yi Liu, Zelin Ma, Shuxiao Ma, Zihuai Wang, Min Yi, Lunxu Liu   +6 more
wiley   +1 more source

The Determination of the Stability Constant of Finasteride Complexes with Various Metals by Potentiometric and Spectrophotometric Methods

, 2016
In this study, the stability constants of the cobalt(II), zinc(II), cadmium(II) and copper(II) complexes of finasteride were determined potentiometrically by using Irving-Rossotti and Calvin-Bjerrum methods and supported by spectrophotometric way [1-3 ...
KARADERİ, SERAP, CÜCÜ, AYŞEN
core   +1 more source