Results 61 to 70 of about 16,896 (199)
ABSTRACT RU 58841 is a nonsteroidal antiandrogen, developed for the treatment of androgen‐dependent conditions. This study aimed to characterize the human metabolism of RU 58841 for the first time and to assess its systemic exposure following topical administration.
Aylin Okutan +4 more
wiley +1 more source
5-alpha-reductase is involved as a rate-imitating enzyme in the metabolism of steroids. Several 5-alpha-reduced steroids such as dihydrotestosterone, allopregnanolone or tetrahydrocorticosterone have neurotrophic, neuroprotective, and anxiolytic ...
Römer, Benedikt, Gass, Peter
core +1 more source
Supplementary Material for: Finasteride and Suicide: A Postmarketing Case Series
Background: In 2011, depression was added to the product labeling of finasteride in the USA. The US Food and Drug Administration’s Adverse Event Reporting System database contains at least 36 death cases for finasteride.
Irwig M.S. (8297481)
core +1 more source
Cognitive effects of testosterone and finasteride administration in older hypogonadal men
Stephen E Borst,1 Joshua F Yarrow,2 Carmen Fernandez,1 Christine F Conover,2 Fan Ye,2 John R Meuleman,1 Matthew Morrow,3 Baiming Zou,4 Jonathan J Shuster5 1Geriatric Research, Education and Clinical Center, 2Research Service, 3Pharmacy Service, Malcom ...
Yarrow JF +8 more
core
FINASTERIDE-ASSOCIATED MALE INFERTILITY
Finasteride is a potent and specific inhibitor of the 5α-reductase enzyme in men. Clinical studies have shown that finasteride 1mg/day is effective for promoting hair growth in men with male pattern hair loss. However, there is a concern about the use of
Saade, Ricardo +12 more
core
Bo Ram Choi,1–3 Hye Kyung Kim,4,* Kiran Kumar Soni,1–3 Keshab Kumar Karna,1–3 Sung Won Lee,5 Insuk So,6 Jong Kwan Park1–3,* 1Department of Urology, Chonbuk National University, Jeonju, Republic of Korea; 2Research Institute of ...
Kim HK +6 more
core
Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date
Wimolsiri Iamsumang, Kanchana Leerunyakul, Poonkiat Suchonwanit Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, ThailandCorrespondence: Poonkiat Suchonwanit Email poonkiat@hotmail ...
Iamsumang W +2 more
doaj
Screening and confirmation methods of the major urinary metabolite of finasteride–carboxy-finasteride for doping control purpose were developed. Liquid–liquid extraction was adopted for the sample preparation.
Jianli Zhang
doaj +1 more source
ABSTRACT Androgenetic alopecia (AGA) is one of the most common causes of hair loss in the male population, characterized by progressive baldness. This study was designed to evaluate the tolerability and local skin pharmacokinetics of bimatoprost in two different formulations in male subjects with AGA.
Sana Khajeh pour +5 more
wiley +1 more source
Use of Topical Finasteride in Hirsutism: A Double-blind, Randomized Clinical Trial on Women
Background: Finasteride partially blocks the conversion of testosterone to dihydrotestosterone through inhibition of 5α-reductase in hair follicles. Finasteride cream can penetrate into the dermis and the hair follicle due to its solubility.
Fariba Iraji +2 more
doaj

