Results 41 to 50 of about 17,467 (192)

Weight Regain After Incretin Treatment: The Lean Mass Deficit Hypothesis and a Role for Testosterone Combination Therapy in Men

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs), dual glucose‐dependent insulinotropic polypeptide (GIP)/GLP‐1RA and triple (GIP)/GLP‐1RA/glucagon agonists achieve placebo‐subtracted weight loss of 15% to 22%. Their long‐term value depends on how well the weight loss is maintained and on the composition of weight loss, not only
Michael Zitzmann   +3 more
wiley   +1 more source

FINASTERIDE (PLUS ORAL CONTRACEPTIVE PILL) VS METFORMIN IN TREATMENT OF POLYCYSTIC OVARY SYNDROME-RELATED INFERTILITY: A PROSPECTIVE RANDOMIZED TRIAL

open access: yesThe Iraqi Journal of Medical Sciences, 2016
Background: Polycystic ovary syndrome (PCOS) is a common endocrinopathy characterized by oligo-ovulation or anovulation, signs of androgen excess, and multiple small ovarian cysts.
Entisar J Al-Mukhtar   +2 more
doaj   +4 more sources

The effect of 3-month finasteride challenge on biomarkers for predicting cancer outcome on biopsy: Results of a randomized trial.

open access: yesPLoS ONE, 2018
BackgroundFinasteride, a 5-alpha reductase inhibitor may have effects on biomarkers such as prostate-specific antigen (PSA) that could be leveraged to improve screening.ObjectiveTo determine the predictive characteristics of biomarkers for prostate ...
Javier Hernandez   +7 more
doaj   +1 more source

Topical Finasteride 0.25% Solution for Female Pattern Hair Loss (FPHL) in Postmenopausal Women: A 52‐Week Retrospective Observational Study

open access: yesInternational Journal of Dermatology, EarlyView.
In this 52‐week retrospective observational study of 26 postmenopausal women with female pattern hair loss, topical finasteride 0.25% monotherapy was associated with significant improvements in hair density (+23.37 hairs/cm2), hair thickness (+10.62 μm), and terminal‐to‐vellus hair ratio (+0.52) (all p < 0.001), providing preliminary observational data
Bianca Maria Piraccini   +7 more
wiley   +1 more source

Understanding Exosomes in Hair Regeneration

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Alopecia is a prevalent condition correlated with significant psychosocial challenges, while contemporary treatments exhibit variable efficacy, require extended use, and may cause adverse effects. This review aimed to comprehensively assess exosome‐mediated interventions as a novel cell‐free regenerative approach for hair ...
Paras Ahmad   +3 more
wiley   +1 more source

Persistent Sexual, Emotional, and Cognitive Impairment Post-Finasteride

open access: yesAmerican Journal of Men's Health, 2015
Finasteride is a synthetic 5-α reductase inhibitor, which prevents the conversion of testosterone to dihydrotestosterone and has been used for more than 20 years in the treatment of male pattern hair loss.
Christine Anne Ganzer PhD   +2 more
doaj   +1 more source

Frozen-Thawed Sperm Analysis of Benign Prostatic Hyperplasia Dogs Treated With Finasteride

open access: yesFrontiers in Veterinary Science, 2022
Benign Prostatic Hyperplasia (BPH) is a pathological condition that directly interferes with the reproductive potential of senile dogs, by leading to prostate enlargement and sperm injury, which in turn may compromise sperm freezeability.
Renato Bueno Flores   +6 more
doaj   +1 more source

Effect of repeated hot water immersion on cognitive performance, cerebrovascular function, sleep and biomarkers of neurodegeneration in older adults

open access: yesExperimental Physiology, EarlyView.
Abstract Ageing is associated with cognitive decline and increased risk of developing neurodegenerative disease. Repeated passive heating, using hot water immersion (HWI), may improve cognitive performance via improved cerebral oxygenation, but this is yet to be examined in older adults.
Daniel D. Piccolo   +16 more
wiley   +1 more source

Synthesis and bioactivity of new Finasteride conjugate

open access: yes, 2011
Finasteride is a synthetic 4-azasteroid compound that acts by inhibiting type II 5 alpha-reductase, the enzyme that converts the androgen testosterone to 5 alpha-dihydrotestosterone.
Li JF   +19 more
core   +1 more source

Effect of repeated hot water immersion on muscle strength, power, function and physical activity in healthy older adults: A randomised crossover trial

open access: yesExperimental Physiology, EarlyView.
Abstract Ageing leads to an increased prevalence of sarcopenia and frailty, characterised by progressive declines in muscle strength, power and function and reduced physical activity. Hot water immersion (HWI) could potentially improve muscle function, but this is yet to be explored in older adults.
Daniel D. Piccolo   +12 more
wiley   +1 more source

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