Results 41 to 50 of about 13,691 (157)

Association between finasteride with subjective memory deficits: a study from the NHANES and FAERS databases

Frontiers in Neurology
BackgroundPostmarketing pharmacovigilance data have raised concerns regarding the potential cognitive effects associated with finasteride administration.
Hao Zhang, Hongqi Ou, Panli Zhao, Xi Luo, Ping Zhang, Hua Huang   +5 more
doaj   +1 more source

Finasteride in the treatment of clinical benign prostatic hyperplasia: A systematic review of randomised trials

BMC Urology, 2002
Background Benign prostatic hyperplasia affects older men. This systematic review determined efficacy and adverse effects of finasteride. Review methods PubMed, the Cochrane Library, reference lists of reports, and reviews were searched for randomised ...
Moore R Andrew, Edwards Jayne E
doaj   +1 more source

Finasteride promotes worsening of the cardiac deleterious effects of nandrolone decanoate and protects against genotoxic and cytotoxic damage

Brazilian Journal of Pharmaceutical Sciences, 2020
Metabolism of anabolic androgenic steroids is important for its physiological effects. The aim was to investigate the effects of finasteride (a 5α-reductase inhibitor - 5αR) on cardiac and mutagenic effects promoted by ND. Male Wistar rats were separated
Elizângela Faustino Da Mata, Andrews Marques do Nascimento, Ewelyne Miranda de Lima, Ieda Carneiro Kalil, Denise Coutinho Endringer, Dominik Lenz, Nazaré Souza Bissoli, Girlandia Alexandre Brasil, Tadeu Uggere de Andrade   +8 more
doaj   +1 more source

Isosorbide dinitrate as an effective adjunct therapy for acute urinary retention: A randomized controlled trial

BJUI Compass, Volume 7, Issue 7, July 2026.
Abstract Objective To evaluate the synergistic effect and safety of sublingual isosorbide dinitrate (ISDN) to facilitate successful voiding trial after catheterization for acute urinary retention (AUR) secondary to benign prostatic hyperplasia (BPH). Material and methods In this randomized clinical trial, male patients aged ≥ 50 years presenting with ...
Salman Soltani, Hamid Reza Ghorbani, Mahmoud Tavakkoli, Fatemeh Sadabadi, Seyyed Parham Ahmadi, Farid Zeinali   +5 more
wiley   +1 more source

Topical Finasteride in Hirsutism: A Double Blind Randomized Clinical Trial on Adult Women

Journal of Research in Medical Sciences, 2005
Background: Finasteride partially blocks the conversion of testosterone to dihydrotestosterone through inhibition of 5 α- reductase in hair follicles. Finasteride cream can penetrate to dermis to arrive at hair follicle due to its solubility.
F Iraji, S Karbasioun, A Aminorroaya
doaj  

Efficacy and Safety of Microneedling Combined With Mesotherapy for Androgenic Alopecia: A Retrospective Study Comparing Four Treatment Protocols

Health Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background and Aims Androgenic alopecia (AGA) is a prevalent form of hair loss characterized by progressive miniaturization of hair follicles, significantly impacting patients’ self‐confidence and quality of life. Current FDA‐approved treatments demonstrate limited to moderate efficacy.
Elham Behrangi, Roya Zeinali, Paria Jafari, Zahra Nosrati, Azadeh Goodarzi   +4 more
wiley   +1 more source

Lipid and Foam Cell Accumulation as Novel Pathological Features of Benign Prostatic Hyperplasia

The Prostate, Volume 86, Issue 10, Page 1157-1169, July 2026.
ABSTRACT Background Benign prostatic hyperplasia (BPH) encompasses a heterogeneous set of pathological processes that instigate lower urinary tract symptoms (LUTS). Using a mouse model of steroid hormone imbalance–induced lower urinary tract dysfunction, we identified luminal lipid‐laden foamy macrophages, although their presence and contribution to ...
Dita Julianingsih, Samara V. Silver, Thaissa Horne, Kasun Gunawardena, Savannah Ward, Alicia Malewska, Douglas Strand, Julius Nyalwidhe, Ilya Sobol, Petra Popovics   +9 more
wiley   +1 more source

Post-finasteride syndrome: our current knowledge

Вестник урологии, 2020
5-α reductase inhibitors are effective and commonly used medications for the treatment of benign prostatic hyperplasia. However, there are some questions about the safety of such medications.
A. A. Galushkin, D. G. Likhikh, M. I. Kogan   +2 more
doaj   +1 more source

The Combination of Nigella sativa Oil‐Based Nanoemulsion and Quercetin Alleviates Oxidative Stress From Exogenous Testosterone Through Antioxidant and Anti‐Inflammatory Mechanisms in Rats

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Exogenous testosterone and stress can cause severe oxidative stress and inflammation in the testicles. To combat testicular damage caused by testosterone and stress, we developed a nanoemulsion containing quercetin and black seed oil. This innovative formulation significantly enhanced antioxidant defences, reduced inflammation and prevented ...
Majid Najafi, Negar Panahi, Saeed Hesaraki, Ghasem Akbari   +3 more
wiley   +1 more source

Screening and confirmation methods of the major urinary metabolite of finasteride–carboxy-finasteride by liquid chromatography–mass spectrometry and liquid chromatography–tandem mass spectrometry

Acta Pharmaceutica Sinica B, 2012
Screening and confirmation methods of the major urinary metabolite of finasteride–carboxy-finasteride for doping control purpose were developed. Liquid–liquid extraction was adopted for the sample preparation.
Jianli Zhang
doaj   +1 more source