Results 21 to 30 of about 17,467 (192)
Metabolites, 2020 Male pattern baldness (MPB) has been associated with dihydrotestosterone (DHT) expression. Finasteride treats MPB by inhibiting 5-alpha reductase and blocking DHT production.
Yu Ra Lee +9 more
doaj +1 more source
Pregnancy and neonatal outcome with maternal exposure to finasteride: Case series
Journal of Dermatology and Dermatologic Surgery, 2021 Background: Finasteride, a type II 5-α reductase inhibitor, is approved for the management of benign prostate hyperplasia and male pattern hair loss. Finasteride is used off-label for female pattern hair loss. In utero fetal exposure to finasteride might
Hessah F BinJadeed, Abdulmajeed Alajlan
doaj +1 more source
FINASTERIDE-ASSOCIATED MALE INFERTILITY
, 2004 Finasteride is a potent and specific inhibitor of the 5α-reductase enzyme in men. Clinical studies have shown that finasteride 1mg/day is effective for promoting hair growth in men with male pattern hair loss. However, there is a concern about the use of
Saade, Ricardo +18 more
core +1 more source
, 2014 aComparison between present and pre-finasteride use ASEX scores, 2-sided P value was evaluated by the Mann-Whitney U-test.bTestosterone supplementation post-finasteride was terminated over 1 year before present study entry.
Emanuele Belgrano (588084) +5 more
core +1 more source
The therapeutic effect of finasteride on fibroblasts.
, 2017 (A) Finasteride induced cell death of fibroblasts. (B) Finasteride repressed the transcription of IGF-1 mRNA in fibroblasts in epithelia-fibroblasts co-culture system. (C) The level of IGF-1 protein in the medium of co-culture system was decreased in the
Dongdong Fan (3746623) +5 more
core +1 more source
The World Journal of Men's Health, 2019 Finasteride is primarily used to treat benign prostatic hyperplasia (BPH) and male androgenetic alopecia (MAA). Five-alpha reductase inhibitors (5α-RIs) could induce male sexual dysfunction due to their effects on testosterone and dihydrotestos-terone ...
Yu Seob Shin +3 more
doaj +1 more source
JEADV Clinical Practice, EarlyView.ABSTRACT Background Topical minoxidil is a first‐line treatment for female androgenetic alopecia (FAGA); however, its twice‐daily application, potential for scalp irritation and impact on hair texture can compromise adherence. Although low‐dose oral minoxidil has emerged as a promising alternative, standardized formulations with well‐characterized ...
Dolores Ochoa Mazarro +2 more
wiley +1 more source
Journal of Lipid ResearchFinasteride is commonly prescribed to treat benign prostate hyperplasia and male-pattern baldness in cis men and, more recently, trans individuals. However, the effect of finasteride on cardiovascular disease remains elusive.
Patrick McQueen +7 more
doaj +1 more source
Anti-proliferative activities of finasteride in benign prostate epithelial cells require stromal fibroblasts and c-Jun gene. [PDF]
PLoS ONE, 2017 This study aimed to identify the role of mouse fibroblast-mediated c-Jun and IGF-1 signaling in the therapeutic effect of finasteride on benign prostatic epithelial cells.
Kai Wang +5 more
doaj +1 more source
Urinary Soluble Collagen Levels Are Associated With Moderate/Severe LUTS
The Prostate, EarlyView.ABSTRACT Background Expansion of the stromal compartment of the prostate concurrent with fibroblast activation and increased collagenization is now recognized as a pathobiology likely contributing to Lower Urinary Tract Symptoms (LUTS). However, approaches to quantitatively and, ideally, non‐invasively, assess prostatic collagenization in vivo are not ...
Marissa Sarna‐McCarthy +5 more
wiley +1 more source