Results 11 to 20 of about 13,691 (157)
Metabolites, 2020 Male pattern baldness (MPB) has been associated with dihydrotestosterone (DHT) expression. Finasteride treats MPB by inhibiting 5-alpha reductase and blocking DHT production.
Yu Ra Lee +9 more
doaj +1 more source
The effectiveness of reducing the daily dose of finasteride in men with benign prostatic hyperplasia
BMC Urology, 2002 Background Finasteride, a 5 alpha reductase inhibitor, is an established treatment for benign prostatic hyperplasia. The recommended dosage is 5 mg a day, however case reports have show effectiveness with lower doses.
Geller Jack, Sullivan Michael J
doaj +1 more source
Does treatment with dutasteride or finasteride has impact on renal morphology? Experimental study
Acta Cirúrgica Brasileira, 2021 Purpose: To investigate whether renal modifications occur following treatment with dutasteride or finasteride. Methods: Twenty-four male rats were divided into three groups: control (that received distilled water), dutasteride (0.5 mg/kg/day), and ...
Marcello Henrique Araújo da Silva +4 more
doaj +1 more source
Pregnancy and neonatal outcome with maternal exposure to finasteride: Case series
Journal of Dermatology and Dermatologic Surgery, 2021 Background: Finasteride, a type II 5-α reductase inhibitor, is approved for the management of benign prostate hyperplasia and male pattern hair loss. Finasteride is used off-label for female pattern hair loss. In utero fetal exposure to finasteride might
Hessah F BinJadeed, Abdulmajeed Alajlan
doaj +1 more source
Anti-proliferative activities of finasteride in benign prostate epithelial cells require stromal fibroblasts and c-Jun gene. [PDF]
PLoS ONE, 2017 This study aimed to identify the role of mouse fibroblast-mediated c-Jun and IGF-1 signaling in the therapeutic effect of finasteride on benign prostatic epithelial cells.
Kai Wang +5 more
doaj +1 more source
The World Journal of Men's Health, 2019 Finasteride is primarily used to treat benign prostatic hyperplasia (BPH) and male androgenetic alopecia (MAA). Five-alpha reductase inhibitors (5α-RIs) could induce male sexual dysfunction due to their effects on testosterone and dihydrotestos-terone ...
Yu Seob Shin +3 more
doaj +1 more source
Advanced Science, EarlyView.A disulfide‐sticker strategy, coupled with Ca2+ coordination, drives the hierarchical self‐assembly of a recombinant scallop adhesive protein into fishnet‐like nanostructures, affording a coating with versatile wet adhesion and intrinsic antioxidant activity. This biocompatible coating markedly promotes hair regeneration by activating follicular niches,
Lulu Wang +7 more
wiley +1 more source
Journal of Lipid ResearchFinasteride is commonly prescribed to treat benign prostate hyperplasia and male-pattern baldness in cis men and, more recently, trans individuals. However, the effect of finasteride on cardiovascular disease remains elusive.
Patrick McQueen +7 more
doaj +1 more source
Prevention of Myc‐Driven Prostate Cancer in Mice by Oral Administration of Sulforaphane
Molecular Carcinogenesis, EarlyView.ABSTRACT Prevention is desirable to reduce suffering and death from prostate cancer. However, a clinical‐grade intervention for the prevention of this malignancy is still lacking. This study was undertaken to determine the feasibility of prostate cancer prevention by broccoli constituent sulforaphane (SFN) because epidemiological studies have suggested
Krishna B. Singh +3 more
wiley +1 more source
Sleep Research, EarlyView.Abstract A 41‐year‐old male patient presented with a 13‐year history of recurrent nocturnal penile pain associated with erections during sleep. Over the course of his illness, the patient attended outpatient clinics on 298 occasions and was hospitalized three times. The primary symptom reported was erectile pain occurring during sleep.
Liping Zhang +5 more
wiley +1 more source