Results 81 to 90 of about 1,764,417 (289)

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Consciousness and Fundamental Fine-Tuning [PDF]

The state of fine-tuning debates has overlooked non-theistic personal explanations. Some underexplored accounts appeal to resources in the philosophy of mind, such as a consciousness-first ontology, like panpsychism. Philip Goff defends such a hypothesis
Rickabaugh, Brandon
core   +2 more sources

Fine-tuning and structured prompting strategies for question answering over full-text biomedical research articles.

PLoS ONE
ObjectivesThe ability of large language models (LLMs) to answer targeted scientific questions by synthesizing information from research articles remains an open research challenge.MethodsWe evaluated the effects of fine-tuning and a question-specific ...
Kaiming Tao, Rohit Satija, Jinru Zhou, Zachary A Osman, Vineet Ahluwalia, Chiara Sabatti, Robert W Shafer   +6 more
doaj   +1 more source

Unlocking DINOv2 for Retinal Multi-Disease Classification and Diabetic Retinopathy Grading

IEEE Access
DINOv2 is a large-scale vision transformer-based foundation model pretrained on over 142 million unlabeled natural images. Despite achieving state-of-the-art results on natural images, its transferability to medical tasks remains largely unexplored. This
Lamiaa Abdel-Hamid
doaj   +1 more source

Fine-tuning the search for microsatellites

Journal of Discrete Algorithms, 2013
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Corné de Ridder, Derrick G. Kourie, Bruce W. Watson, T. R. Fourie, P. V. Reyneke   +4 more
openaire   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Neural specialization of print processing in second language learning: A longitudinal ERP study of Chinese children learning English

Developmental Cognitive Neuroscience
The N1 component of event-related potentials (ERP) reflects print tuning and lexicality effects. Previous studies have shown that for a second learned writing system, tuning and lexical effects are associated with age and ability.
Xin Huang, Jai Dellosa Ariza, Shuting Huo, Jason Chor Ming Lo, Catherine McBride, Urs Maurer   +5 more
doaj   +1 more source

Fine-tuning of integrin activation [PDF]

Blood, 2016
In this issue of Blood , [Block et al][1] demonstrate that G protein β subunit (Gβ) isoforms are indispensable for chemokine-induced lymphocyte function-associated antigen 1 (LFA-1) integrin activation and neutrophil arrest mediated by Ras-related C3 botulinum toxin substrate 1 (Rac1 ...
openaire   +2 more sources

Fine-tuning the impairment argument

Journal of Medical Ethics, 2020
Perry Hendricks’ original impairment argument for the immorality of abortion is based on the impairment principle: if impairing an organism to some degree is immoral, thenceteris paribus, impairing it to a higher degree is also immoral. Since abortion impairs a fetus to a higher degree than fetal alcohol syndrome (FAS) and giving a fetus FAS is immoral,
Bruce Philip Blackshaw, Perry Hendricks
openaire   +3 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source