Results 71 to 80 of about 1,764,417 (289)
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Fine-tuned model and USPTO data used in fine-tuning
Fine-tuned model and USPTO data used in fine ...
Qianxiang Ai (18261997)
core +1 more source
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Zasada szczególnego dostrojenia w kontekście układów z chaosem deterministycznym
From the beginning of the deterministic chaos research, the unpredictability has been its central theme. Interesting questions arise here: What are the consequences of chaos for the fine tuned processes? Are there fine tuning systems in reality?
Bartłomiej Brus, Marek Szydłowski
doaj
SAM-FGF: SAM fine grained fine-tuning for ophthalmic image segmentation
With increasing reliance on multi-structural analysis in ophthalmic diagnosis and treatment, accurate segmentation of ocular structures and lesions is essential for effective clinical decision-making. Multi-modal imaging, such as color fundus photography
Yuancong Liang +7 more
doaj +1 more source
The Fine-Tuning Of The Universe For Life [PDF]
15 pages, 1 figure. Invited contribution to the Routledge Companion to Philosophy of Physics, edited By Eleanor Knox, Alastair ...
openaire +3 more sources
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
A Resource-Efficient Approach to Fine-Tuning a BERT-Base Model for Sentiment Analysis
Fine-tuning a BERT-Base model for specific tasks, such as sentiment analysis, has become resource-intensive and often requires high computational power and memory.
Abdullah M. Basahel +5 more
doaj +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source

