Results 51 to 60 of about 1,262,485 (305)

OPTIMIZING ULTRASOUND IMAGE CLASSIFICATION THROUGH TRANSFER LEARNING: FINE-TUNING STRATEGIES AND CLASSIFIER IMPACT ON PRE-TRAINED INNER-LAYERS

open access: yesInformatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2023
Transfer Learning (TL) is a popular deep learning technique used in medical image analysis, especially when data is limited. It leverages pre-trained knowledge from State-Of-The-Art (SOTA) models and applies it to specific applications through Fine ...
Mohamed Bal-Ghaoui   +3 more
doaj   +1 more source

Cosmological fine-tuning arguments what (if anything) should we infer from the fine-tuning of our universe for life?

open access: yes, 2020
"If the physical constants, initial conditions, or laws of nature in our universe had been even slightly different, then the evolution of life would have been impossible.
Waller, Jason 1980-
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

LLM Fine-Tuning: Concepts, Opportunities, and Challenges

open access: yesBig Data and Cognitive Computing
As a foundation of large language models, fine-tuning drives rapid progress, broad applicability, and profound impacts on human–AI collaboration, surpassing earlier technological advancements.
Xiao-Kun Wu   +18 more
doaj   +1 more source

Measuring the Instability of Fine-Tuning

open access: yesProceedings of the 61st Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers), 2023
Fine-tuning pre-trained language models on downstream tasks with varying random seeds has been shown to be unstable, especially on small datasets. Many previous studies have investigated this instability and proposed methods to mitigate it. However, most studies only used the standard deviation of performance scores (SD) as their measure, which is a ...
Yupei Du, Dong Nguyen 0002
openaire   +4 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

The Fine-Tuning Of The Universe For Life [PDF]

open access: yes, 2021
15 pages, 1 figure. Invited contribution to the Routledge Companion to Philosophy of Physics, edited By Eleanor Knox, Alastair ...
openaire   +3 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Fine-tuning protein language models boosts predictions across diverse tasks

open access: yesNature Communications
Prediction methods inputting embeddings from protein language models have reached or even surpassed state-of-the-art performance on many protein prediction tasks.
Robert Schmirler   +2 more
doaj   +1 more source

A Resource-Efficient Approach to Fine-Tuning a BERT-Base Model for Sentiment Analysis

open access: yesComputers
Fine-tuning a BERT-Base model for specific tasks, such as sentiment analysis, has become resource-intensive and often requires high computational power and memory.
Abdullah M. Basahel   +5 more
doaj   +1 more source

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